Convallatoxin, the primary cardiac glycoside in lily of the valley (Convallaria majalis), induces tissue factor expression in endothelial cells.
Mami MorimotoKohei TatsumiKatsuya YuuiIkuko TerazawaRisa KudoShogo KasudaPublished in: Veterinary medicine and science (2021)
TF expression induced by CNT in endothelial cells can contribute to the development of a hypercoagulable state. The present study partially revealed the mechanisms underlying the CNT-induced hypercoagulable state. The findings can contribute to the development of a novel therapy for lily of the valley poisoning.