Clinical evaluation of efficacy, safety and tolerability of cysteamine 5% cream in comparison with modified Kligman's formula in subjects with epidermal melasma: A randomized, double-blind clinical trial study.

Maryam KarrabiJennifer DavidMohammad Sahebkar

Published in: Skin research and technology : official journal of International Society for Bioengineering and the Skin (ISBS) [and] International Society for Digital Imaging of Skin (ISDIS) [and] International Society for Skin Imaging (ISSI) (2020)

Cysteamine 5% cream showed greater efficacy as compared to MKF. It is thus proposed that cysteamine 5% cream is more effective than MKF in the treatment of melasma, with the advantage of being significantly better tolerated.

Keyphrases

clinical evaluation
double blind
clinical trial
placebo controlled
open label
phase ii
study protocol
phase iii
randomized controlled trial
human milk
combination therapy
preterm infants
replacement therapy
preterm birth
low birth weight