Changes of colistin pharmacokinetics in critically ill patients due to the extracorporeal membrane oxygenation: protocol for the COL-ECMO2022 trial - a prospective, non-randomised, open-label phase IV pharmacokinetic clinical trial.
Pavel SukJitka RychlíčkováLenka SoučkováVendula KubíčkováKarel UrbánekPublished in: BMJ open (2023)
EudraCT Number 2022-000291-19; NCT05542446.
Keyphrases
- extracorporeal membrane oxygenation
- open label
- clinical trial
- phase ii
- phase iii
- study protocol
- acute respiratory distress syndrome
- escherichia coli
- randomized controlled trial
- acinetobacter baumannii
- pseudomonas aeruginosa
- phase ii study
- klebsiella pneumoniae
- respiratory failure
- multidrug resistant
- gram negative
- drug resistant
- double blind
- placebo controlled
- intensive care unit
- locally advanced