HHV-6A infection induces amyloid-beta expression and activation of microglial cells.

Daria BortolottiValentina GentiliAntonella RotolaElisabetta CaselliRoberta Rizzo

Published in: Alzheimer's research & therapy (2019)

In conclusion, microglial cells are permissive to HHV-6A infection that induces the expression of Aβ and an activation status. Meanwhile, we hypothesize a paracrine effect of HHV-6A infection that activates and induces microglia migration to the site of infection.

Keyphrases

induced apoptosis
poor prognosis
inflammatory response
neuropathic pain
lps induced
endoplasmic reticulum stress
long non coding rna