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A new monocyte epigenetic clock reveals nonlinear effects of alcohol consumption on biological aging in three independent cohorts (N = 2242).

Xiaoyu LiangRajita SinhaAmy C JusticeMardge H CohenBradley E AouizeratKe Xu
Published in: Alcoholism, clinical and experimental research (2022)
The results suggest a nonlinear relationship between alcohol consumption and its effects on epigenetic age. Considering adverse effects of alcohol consumption on health, nonlinear effects of alcohol use should be interpreted with caution. The findings, for the first time, highlight the complex effects of alcohol consumption on biological aging.
Keyphrases
  • alcohol consumption
  • dna methylation
  • gene expression
  • healthcare
  • public health
  • dendritic cells
  • health information
  • immune response
  • endothelial cells
  • risk assessment
  • peripheral blood
  • social media
  • climate change