Low ferroptosis score predicts chemotherapy responsiveness and immune-activation in colorectal cancer.

Cheng HuangQing-Yang FengZhi-Yuan ZhangPeng ZhengDe-Xiang ZhuQi LinSi-Min ChenYi-Hao MaoYu-Qiu XuMei-Ling JiJian-Min XuGuo-Dong He

Published in: Cancer medicine (2022)

Ferroptosis plays important role on CRC tumor progression, ACT response and prognosis. Ferroptosis contributes to immune-supportive responses and IFN-γ was the central molecule for this process.

Keyphrases

cell death
immune response
poor prognosis
locally advanced
radiation therapy