Sex Differences in the Relationship between New York Heart Association Functional Classification and Survival in Cardiovascular Disease Patients: A Mediation Analysis of Exercise Capacity with Regular Care Data.
Klaske R SiegersmaNiels A StensFloor GroepenhoffYolande AppelmanIgor I TulevskiLeonard HofstraHester M den RuijterG Aernout SomsenN Charlotte Onland-MoretPublished in: Reviews in cardiovascular medicine (2022)
This study showed a significant mediation in both sexes on the association between NYHA functional class and all-cause mortality by proportional workload, but the effect explained by NYHA classification on the association between survival and proportional workload is small. This implies that NYHA classification is not a sole representation of a patient's functional capacity, but might also incude other aspects of the patient's overall health status.
Keyphrases
- machine learning
- deep learning
- cardiovascular disease
- end stage renal disease
- case report
- ejection fraction
- healthcare
- chronic kidney disease
- social support
- palliative care
- peritoneal dialysis
- heart failure
- physical activity
- prognostic factors
- free survival
- metabolic syndrome
- high intensity
- atrial fibrillation
- electronic health record
- quality improvement
- pain management
- patient reported outcomes