Effect of silibinin on the expression of MMP2, MMP3, MMP9 and TIMP2 in kidney and lung after hepatic ischemia/reperfusion injury in an experimental rat model.

Vasileios Kollaras Georgia Valsami Maria Lambropoulou Ourania Konstandi Nikolaos G Kostomitsopoulos Emmanouil Pikoulis Constantinos Simopoulos Alexandra K Tsaroucha

Published in: Acta cirurgica brasileira (2021)

Hepatic IRI causes distant kidney and lung damage, while a statistically significant protective action, both on kidney and lung parenchyma, is conveyed by the intravenous administration of silibinin.

Keyphrases

cell migration
poor prognosis
lymph node
oxidative stress
low dose
binding protein
long non coding rna