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Very long-term outcomes after a single catheter ablation procedure for the treatment of atrial fibrillation-the protective role of antiarrhythmic drug therapy.

João MesquitaDiogo CavacoAntónio Miguel FerreiraFrancisco Moscoso CostaPedro CarmoFrancisco MorgadoMiguel MendesPedro Adragão
Published in: Journal of interventional cardiac electrophysiology : an international journal of arrhythmias and pacing (2018)
Half the patients remained free from AF 5 years after a single procedure. Female sex, non-paroxysmal AF, and LA volume/BSA independently predicted recurrence, whereas continuing AAD after the 3-month blanking period reduced relapse. In a multicenter registry of AF patients undergoing a first PVI, 57% relapsed over a median 5-year follow-up. Female sex, non-paroxysmal AF and LA volume/BSA were identified as independent predictors of relapse. Maintaining AAD therapy after the blanking period was associated with a long-term reduction in AF relapse.
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