Longitudinal Systemic and Mucosal Immune Responses to SARS-CoV-2 Infection.

Peter F WrightAlejandra C Prevost-ReillyHarini NatarajanElizabeth Bailey BrickleyRuth I ConnorWendy F Wieland-AlterAnna S MieleJoshua A WeinerRobert D NerenzMargaret E Ackerman

Published in: The Journal of infectious diseases (2022)

Sustained antibody responses occurred after SARS-CoV-2 infection. Notably, there was independent induction of IgM and IgA binding antibody and neutralizing responses in systemic and respiratory compartments. These observations have implications for current vaccine strategies and understanding SARS-CoV-2 reinfection and transmission.

Keyphrases

respiratory syndrome coronavirus
sars cov
immune response
coronavirus disease
cross sectional
dendritic cells
toll like receptor
inflammatory response
drug induced
dna binding
aedes aegypti