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Randomized controlled trial of twin-twin transfusion syndrome laser surgery: the sequential trial.

Ramen H ChmaitLisa M KorstArlyn S LlanesKristine R RalloAndrew H ChonMartha A MonsonMoshe FridmanRubén A Quintero
Published in: American journal of obstetrics and gynecology (2024)
Donor twin survival did not differ between the sequential vs selective laser techniques and did not differ if superficial anastomoses were ablated first vs last. The donor twin's postoperative middle cerebral artery peak systolic velocity was improved with the sequential vs the selective approach. Post hoc analyses suggest that donor twin survival may be associated with the choice of laser technique according to high-risk factors. Further study is needed to determine whether using these categories to guide the choice of surgical technique will improve outcomes.
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