Deciphering the role of epigenetic modifications in fatty liver disease: A systematic review.

Xiaofang ZhangEralda AsllanajMasoud AmiriEliana Portilla-FernandezWichor M BramerJana NanoTrudy VoortmanMaikel P Peppelenbosch Mohsen Ghanbari

Published in: European journal of clinical investigation (2021)

Cumulative evidence suggests a link between epigenetic mechanisms, specifically DNA methylation and miRNAs, and FLD. Further efforts should investigate the molecular pathways by which these epigenetic markers may regulate FLD and also the potential role of histone modifications in FLD.

Keyphrases

dna methylation
gene expression
genome wide
copy number
climate change
fatty acid