Outcome of Children and Adolescents With Primary Intracranial Germinoma Treated With Chemotherapy and Reduced Dose-Field Irradiation: A Prospective Brazilian Experience.
Andrea Maria CappellanoNatalia DassiBruna Minniti MançanoSidnei EpelmanDaniela B AlmeidaSergio CavalheiroPatricia Alessandra DastoliMaria Teresa Seixas AlvesJardel M NicacioMarcos Devanir Silva da CostaFrederico A SilvaSimone S AguiarCarlos Roberto Almeida JuniorGustavo R TeixeiraMichael Jenwei ChenMaria Luisa FigueiredoNasjla S SilvaJonathan L FinlayPublished in: JCO global oncology (2023)
The treatment is tolerable, and WVFI dose reduction to 18 Gy preserves efficacy; we have demonstrated the feasibility of successfully conducting a prospective multicenter trial in a large MIC despite resource disparity.