AIM2 promotes irradiation resistance, migration ability and PD-L1 expression through STAT1/NF-κB activation in oral squamous cell carcinoma.

Hui-Wen ChiuHsin-Lun LeeHsun-Hua LeeHsiao-Wei LuKent Yu-Hsien LinYuan-Feng LinChe-Hsuan Lin

Published in: Journal of translational medicine (2024)

Our data unveil AIM2 as a critical factor for promoting radioresistance, metastasis and PD-L1 expression and as a potential biomarker for predicting ICI effectiveness on the refractory OSCC.

Keyphrases

signaling pathway
randomized controlled trial
systematic review
lps induced
cell proliferation
big data
pi k akt
oxidative stress
dna damage response
nuclear factor
radiation induced
cancer stem cells
machine learning
artificial intelligence
toll like receptor