A protocol of trial of ivermectin in COVID-19 treatment critically changed after its completion.

We read the article by Abd-Elsalam et al. 1 in Journal of Medical Virology with great interest. The authors conducted a randomized controlled trial to evaluate the efficacy of ivermectin for COVID-19 infected patients. They demonstrated shorter length of hospital stay in ivermectin group than that in group without ivermectin, but the difference was not statistically significant. We have several concerns on this study regarding with study protocol and statistical analyses. This article is protected by copyright. All rights reserved.