Controlling transmembrane protein concentration and orientation in supported lipid bilayers.

Peng BaoM L CartronK H SheikhB R G JohnsonC N HunterS D Evans

Published in: Chemical communications (Cambridge, England) (2018)

The trans-membrane protein - proteorhodopsin (pR) has been incorporated into supported lipid bilayers (SLB). In-plane electric fields have been used to manipulate the orientation and concentration of these proteins, within the SLB, through electrophoresis leading to a 25-fold increase concentration of pR.

Keyphrases

molecular dynamics simulations
fatty acid
protein protein
small molecule