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Methyl β-Cyclodextrin-sperm-mediated gene editing (MBCD-SMGE): a simple and efficient method for targeted mutant mouse production.

Parisa MoradbeigiSara HosseiniMohammad SalehiAsghar Mogheiseh
Published in: Biological procedures online (2024)
Overall, this study highlights the significant potential of the MBCD-SMGE technique for generating targeted mutant mice. It holds enormous promise for modeling human diseases and improving desirable traits in animals.
Keyphrases
  • wild type
  • endothelial cells
  • cancer therapy
  • genome wide
  • ionic liquid
  • high fat diet induced
  • risk assessment
  • gene expression
  • pluripotent stem cells
  • adipose tissue
  • dna methylation
  • deep learning