Dexamethasone vs COVID-19: An experimental study in line with the preliminary findings of a large trial.
Mohammad Hossein HosseinzadehAmir ShamshirianMohammad Ali EbrahimzadehPublished in: International journal of clinical practice (2020)
This experimental in vivo investigation demonstrated an excellent protective effect for 10 days of dexamethasone treatment against hypoxia, especially in asphyctic and hemic models. In addition to promising dexamethasone outcomes, using propranolol as the positive control illustrated a very substantial anti-hypoxic effect even much better than dexamethasone in all models. It seems that propranolol would be a safe, potential, and prudent choice to invest in treating COVID-19 patients.