A Convenient, Rapid, Conventional Heating Route to MIDA Boronates.
Andrew McGownAnthony K EdmondsDaniel GuestVerity L HolmesChris DadswellRamón González-MéndezCharles A I GoodallMark C BagleyBarnaby W GreenlandJohn SpencerPublished in: Molecules (Basel, Switzerland) (2022)
A cheap, conventional, sealed heating reactor proved to be a useful alternative to a microwave reactor in the synthesis of a >20-member MIDA boronate library (MIDA = N- methyliminodiacetic acid). Reaction times were 10 min and work-ups were minimal, saving on energy and solvent usage.