Phase 1 clinical study of cell therapy with effective-mononuclear cells (E-MNC) for radiogenic xerostomia (first-in-human study) (FIH study on E-MNC therapy for radiogenic xerostomia).

Yoshinori SumitaNaoki IwamotoMakoto SekiTakako YoshidaRyo HonmaMayumi IwatakeSeigo OhbaI TakashiYuka HotokezakaHiroshi HaradaShinichiro KuroshimaKazuhiro NagaiTakayuki AsaharaI Atsushi KawakamIzumi Asahina

Published in: Medicine (2020)

This study was registered with the Japan Registry of Clinical Trials (http://jrct.niph.go.jp) as jRCTb070190057.

Keyphrases

cell therapy
clinical trial
stem cells
randomized controlled trial
mesenchymal stem cells
bone marrow
signaling pathway
oxidative stress