COVID-19 and the Brain: The Neuropathological Italian Experience on 33 Adult Autopsies.

Viscardo P FabbriMattia RiefoloLazzarotto Tiziana Liliana Gabrielli Giovanna CenacchiCarmine GalloRaffaele AspideGuido FrascaroliRocco LiguoriRaffaele LodiCaterina TononAntonietta D'ErricoMaria Pia Foschini

Published in: Biomolecules (2022)

Neurological symptoms are increasingly recognized in SARS-CoV-2 infected individuals. However, the neuropathogenesis remains unclear and it is not possible to define a specific damage pattern due to brain virus infection. In the present study, 33 cases of brain autopsies performed during the first (February-April 2020) and the second/third (November 2020-April 2021) pandemic waves are described. In all the cases, SARS-CoV-2 RNA was searched. Pathological findings are described and compared with those presently published.

Keyphrases

sars cov
respiratory syndrome coronavirus
resting state
white matter
coronavirus disease
cerebral ischemia
functional connectivity
systematic review
oxidative stress
randomized controlled trial
subarachnoid hemorrhage
sleep quality
meta analyses