Genome-wide enhancer RNA profiling adds molecular links between genetic variation and human cancers.

Yi-Min CaiZe-Qun LuBin LiJin-Yu HuangMing ZhangCan ChenLin-Yun FanQian-Ying MaChun-Yi HeShuo-Ni ChenYuan JiangYan-Min LiCai-Bo NingFu-Wei ZhangWen-Zhuo WangYi-Zhuo LiuHeng ZhangMeng JinXiao-Yang WangJin-Xin HanZhen XiongMing CaiChao-Qun HuangXiao-Jun YangXu ZhuYing ZhuXiao-Ping MiaoShao-Kai ZhangYong-Chang WeiJian-Bo Tian

Published in: Military Medical Research (2024)

Our findings underscore the significance of eRNAQTLs in transcriptional regulation and disease heritability, pinpointing the potential of eRNA-based therapeutic strategies in cancers.

Keyphrases

genome wide
endothelial cells
dna methylation
pluripotent stem cells
binding protein
single cell
human health
single molecule
copy number
risk assessment
young adults