A human monoclonal antibody blocking SARS-CoV-2 infection.
Chunyan WangWentao LiDubravka DrabekNisreen M A OkbaRien van HaperenAlbert D M E OsterhausFrank J M van KuppeveldBart L HaagmansFrank GrosveldBerend-Jan BoschPublished in: Nature communications (2020)
The emergence of the novel human coronavirus SARS-CoV-2 in Wuhan, China has caused a worldwide epidemic of respiratory disease (COVID-19). Vaccines and targeted therapeutics for treatment of this disease are currently lacking. Here we report a human monoclonal antibody that neutralizes SARS-CoV-2 (and SARS-CoV) in cell culture. This cross-neutralizing antibody targets a communal epitope on these viruses and may offer potential for prevention and treatment of COVID-19.