Inflammatory subphenotypes in patients at risk of ARDS: evidence from the LIPS-A trial.

Simone Redaelli Dario von WedelMaxime FossetAiman M Suleiman Guanqing ChenJulie AlingrinMichelle Ng Gong Ognjen Gajic Valerie M Banner-Goodspeed Daniel Talmor Maximilian S Schaefer Boris Jung

Published in: Intensive care medicine (2023)

Hyper- and non-hyper-inflammatory subphenotypes may precede ARDS development, remain identifiable over time, and can be identified upon presentation to the emergency department. A hyper-inflammatory subphenotype predicts worse outcomes.

Keyphrases

emergency department
oxidative stress
acute respiratory distress syndrome
extracorporeal membrane oxygenation
mechanical ventilation
clinical trial
study protocol
randomized controlled trial
type diabetes
phase iii
case report
skeletal muscle
insulin resistance