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Hypoxia-Regulated Proteins: Expression in Endometrial Cancer and Their Association with Clinicopathologic Features.

Dae Hyun SongJae Yoon JoCho Hee KimMin Hye KimIn Ae ChoJeong Kyu ShinWon Jun ChoiJong Chul Baek
Published in: Diagnostics (Basel, Switzerland) (2024)
A higher proportion of HIF-1α-positive immune cells is associated with endometrial cancers with higher histologic grade and diffuse GLUT1 expression patterns. These findings suggest a potential role for HIF-1α as a prognostic marker and highlight the need for further studies into the role of HIF-1α in the tumor microenvironment.
Keyphrases
  • endometrial cancer
  • poor prognosis
  • endothelial cells
  • binding protein
  • transcription factor
  • long non coding rna