Associations of Transcription Factor 21 Gene Polymorphisms with the Growth and Body Composition Traits in Broilers.
Linyong ShenJiaqiang YuYaowen GeHui LiYumao LiZhiping CaoPeng LuanFan XiaoHaihe GaoHui ZhangPublished in: Animals : an open access journal from MDPI (2022)
This study aims to identify molecular marker loci that could be applied in broiler breeding programs. In this study, we used public databases to locate the Transcription factor 21 ( TCF21 ) gene that affected the economically important traits in broilers. Ten single nucleotide polymorphisms were detected in the TCF21 gene by monoclonal sequencing. The polymorphisms of these 10 SNPs in the TCF21 gene were significantly associated ( p < 0.05) with multiple growth and body composition traits. Furthermore, the TT genotype of g.-911T>G was identified to significantly increase the heart weight trait without affecting the negative traits, such as abdominal fat and reproduction by multiple methods. Thus, it was speculated that the g.-911T>G identified in the TCF21 gene might be used in marker-assisted selection in the broiler breeding program.
Keyphrases
- genome wide
- body composition
- dna methylation
- transcription factor
- copy number
- resistance training
- genome wide identification
- bone mineral density
- heat stress
- heart failure
- healthcare
- gene expression
- body mass index
- public health
- adipose tissue
- mental health
- machine learning
- single cell
- physical activity
- fatty acid
- weight gain
- big data
- genome wide association
- deep learning