Evolution of Fatty Liver Disease and Relationship With Lipoproteins and Clinical Outcomes in Hepatitis B/Human Immunodeficiency Virus Coinfection.

Mandana KhaliliWendy C KingDavid E KleinerRaymond T ChungAtul K BhanMarc G GhanyMark S SulkowskiMauricio Lisker-MelmanMamta K JainHarry L A JanssenAmanda S HinermanArun J SanyalRichard K Sterling

Published in: Clinical infectious diseases : an official publication of the Infectious Diseases Society of America (2021)

In this cohort, there was no significant change in FLD prevalence over a relatively short timeframe. Baseline atherogenic lipids appeared highest in those with persistent steatosis or steatohepatitis, suggesting potentially increased cardiovascular risk in this group, but an independent relationship between individual-level change in FLD status and lipid/lipoprotein levels across follow-up was not observed.

Keyphrases

human immunodeficiency virus
hepatitis c virus
antiretroviral therapy
fatty acid
hiv infected
risk factors
hiv aids
low density lipoprotein
insulin resistance
hiv positive
type diabetes
metabolic syndrome
adipose tissue
skeletal muscle
high fat diet induced
liver fibrosis