Tissue factor upregulation is associated with SARS-CoV-2 in the lungs of COVID-19 patients.

Sandeep SubrahmanianAlain BorczukSteven SalvatoreKar-Ming FungJoan T MerrillJeffrey Laurence Jasimuddin Ahamed

Published in: Journal of thrombosis and haemostasis : JTH (2021)

These data suggest that upregulation of TF expression is associated with thrombus formation in COVID-19 lungs and could be a key therapeutic target. Correlation of TF expression with SARS-CoV-2 in lungs of COVID-19 patients also raises the possibility of direct TF induction by the virus.

Keyphrases

sars cov
poor prognosis
respiratory syndrome coronavirus
long non coding rna
cell proliferation
binding protein
coronavirus disease
big data
artificial intelligence