Maternal metabolic profiling across body mass index groups: An exploratory longitudinal study.
Hege Nyhus SkytteMarie Cecilie Paasche RolandJacob Juel ChristensenKirsten Bjørklund HolvenTove LekvaNina GunnesTrond Melbye MichelsenPublished in: Acta obstetricia et gynecologica Scandinavica (2023)
Overweight or obese women had smaller pregnancy-related metabolic alterations than normal-weight/underweight women. There was a trend toward higher triglyceride and VLDL particle concentration in overweight/obese women. As this was a hypothesis-generating study, the similarities with late-onset pre-eclampsia warrant further investigation. The unfavorable development of fatty acid composition in overweight/obese women, with possible implication for the offspring, should also be studied further in the future.
Keyphrases
- weight loss
- pregnancy outcomes
- late onset
- weight gain
- body mass index
- polycystic ovary syndrome
- bariatric surgery
- physical activity
- adipose tissue
- metabolic syndrome
- type diabetes
- birth weight
- fatty acid
- early onset
- pregnant women
- cervical cancer screening
- obese patients
- insulin resistance
- high fat diet
- breast cancer risk
- preterm birth
- drug induced
- solid state