Lampaya Medicinalis Phil. decreases lipid-induced triglyceride accumulation and proinflammatory markers in human hepatocytes and fat body of Drosophila melanogaster.

Sofía Sanhueza Nicolás TobarMariana CifuentesDaniela Quenti Rosaria Varì Beatrice Scazzocchio Roberta Masella Karin Herrera Adrián ParedesGlauco MoralesPaulina Ormazabal

Published in: International journal of obesity (2005) (2021)

HEL effect counteracting OA/PA- and HFD-induced lipid accumulation and proinflammatory marker expression in HepG2 hepatocytes and Drosophila larvae may represent a preventive approach against hepatic steatosis and inflammation, associated to obesity and NAFLD.

Keyphrases

drosophila melanogaster
high glucose
endothelial cells
diabetic rats
drug induced
liver injury
oxidative stress
poor prognosis
metabolic syndrome
type diabetes
insulin resistance
adipose tissue
weight loss
high fat diet
weight gain
physical activity
binding protein
long non coding rna
high fat diet induced