Functionalized Graphene Nanoparticles Induce Human Mesenchymal Stem Cells to Express Distinct Extracellular Matrix Proteins Mediating Osteogenesis.
Steven D NewbyTom MasiChristopher D GriffinWilliam J KingAnna ChipmanStacy StephensonDavid Edger AndersonAlexandru S BirisShawn E BourdoMadhu S DharPublished in: International journal of nanomedicine (2020)
Understanding the cell-graphene interactions resulting in an osteogenic niche for MSCs will significantly improve the application of graphene nanoparticles in bone repair and regeneration.
Keyphrases
- mesenchymal stem cells
- extracellular matrix
- walled carbon nanotubes
- umbilical cord
- cell therapy
- room temperature
- bone marrow
- endothelial cells
- carbon nanotubes
- stem cells
- single cell
- bone mineral density
- pluripotent stem cells
- induced pluripotent stem cells
- soft tissue
- wound healing
- body composition
- molecularly imprinted