Effect of irisin on the expression of osteoclast-related genes in cementoblasts.

Chunyi ZhaoYunlong WangZhengguo CaoJiaqi ZhuHong He

Published in: European journal of orthodontics (2022)

OCCM-30 cells were responsive to the stimulation of irisin. The expression of RANKL and IL-6 was significantly enhanced by irisin, suggesting a possible promotive effect on cementoblast-mediated osteoclastogenesis.

Keyphrases

poor prognosis
bone loss
induced apoptosis
cell cycle arrest
cancer therapy
long non coding rna
drug delivery
signaling pathway
cell proliferation
endoplasmic reticulum stress
toll like receptor