Cancer Cell Models for the Development of Anti-Cancer Drugs.

Published in: International journal of molecular sciences (2022)

In the multi-factorial etiology of organ-site cancers by suspect human chemical carcinogens, oncogenic virus, activation of RAS, Myc and HER-2 oncogenes, inactivation of TP53, RB and APC tumor suppressor genes represent early-occurring genetic events [...].

Keyphrases

genome wide
endothelial cells
transcription factor
induced pluripotent stem cells
pluripotent stem cells
copy number
wild type
gene expression
bioinformatics analysis
young adults
genome wide analysis
disease virus