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Characterising the molecular epidemiology of human parechovirus in young infants in the UK and Canada.

Seilesh KadambariHeli HarvalaDung NguyenManish SadaranganiNatalie G MartinGhada N Al-RawahiInna SekirovSylviane DefresTom SolomonTanya GolubchikRory BowdenAndrew J PollardPeter Simmonds
Published in: Journal of clinical virology : the official publication of the Pan American Society for Clinical Virology (2024)
In this small cohort, sequencing data indicate that PeV circulating in the UK and Canada from 2013 to 18 are derived from a common ancestor. No association between disease severity and genetic sequence was seen in the UK or Canadian cohorts. Larger studies are required to support these findings.
Keyphrases
  • cross sectional
  • endothelial cells
  • single cell
  • genome wide
  • gene expression
  • induced pluripotent stem cells
  • big data
  • dna methylation
  • case control