Sex-Based Dimorphism of Anticancer Immune Response and Molecular Mechanisms of Immune Evasion.
Fabio ConfortiLaura PalaEleonora PaganVincenzo BagnardiTommaso Martino De PasPaola QueiroloElisabetta PennacchioliChiara CataniaEmilia CocorocchioPier Francesco FerrucciMaristella SaponaraGianmarco OrsoliniPaola ZagamiEleonora NicolóFilippo De MarinisGiampaolo TortoraEmilio BriaSaverio MinucciHadine JoffePaolo VeronesiJennifer WargoRachel RosenthalCharles SwantonAlberto MantovaniRichard D GelberGiuseppe VialeAron GoldhirschGiuseppe GiacconePublished in: Clinical cancer research : an official journal of the American Association for Cancer Research (2021)
We demonstrated meaningful sex-based differences of anticancer immune response and immune evasion mechanisms, that may be exploited to improve immunotherapy efficacy for both women and men.