Charles Swanton

Scopus Author ID ORCID

Publication Activity (10 Years)

Years Active: 2018-2024
Publications (10 Years): 129

Top Venues

Nature communications

Nature cancer

Cancer discovery

Nature

Cancer Research UK

University College Medical School (PHD)

This page only lists publications with an associated author ORCID identifier.

Affiliation History

Cancer Research UK Oct 01 2017

United Kingdom

Chief Clinician

UCL Cancer Institute Jul 01 2011

United Kingdom

Senior Group Leader :: Cancer Evolution and Genome Instability Laboratory

Francis Crick Institute May 01 2008

United Kingdom

Senior Group Leader :: Cancer Evolution and Genome Instability Laboratory

Education History

University College Medical School

United Kingdom

PHD

Imperial Cancer Research Fund

United Kingdom

PHD

Publications

Alastair Magness, Emma C Colliver, Katey S S Enfield, Claudia S Y Lee, Masako Shimato, Emer Daly, David Allan Moore, Monica Sivakumar, Karishma Valand, Dina Levi, Crispin T Hiley, Philip S Hobson, Febe van Maldegem, James L Reading, Sergio A Quezada, Julian Downward, Erik Sahai, Charles Swanton, Mihaela Angelova
Deep cell phenotyping and spatial analysis of multiplexed imaging with TRACERx-PHLEX. Nature communications 15 (1) (2024)
Michelle Dietzen, Haoran Zhai, Olivia Lucas, Oriol Pich, Christopher Barrington, Wei-Ting Lu, Sophia Ward, Yanping Guo, Robert Edward Hynds, Simone Zaccaria, Charles Swanton, Nicholas McGranahan, Nnennaya Kanu
Replication timing alterations are associated with mutation acquisition during breast and lung cancer evolution. Nature communications 15 (1) (2024)
Robert Edward Hynds, Ariana Huebner, David R Pearce, Mark S Hill, Ayse U Akarca, David Allan Moore, Sophia Ward, Kate H C Gowers, Takahiro Karasaki, Maise Al Bakir, Gareth A Wilson, Oriol Pich, Carlos Martínez-Ruiz, A S Md Mukarram Hossain, Simon P Pearce, Monica Sivakumar, Assma Ben Aissa, Eva Grönroos, Deepak P Chandrasekharan, Krishna K Kolluri, Rebecca Towns, Kaiwen Wang, Daniel E Cook, Leticia Bosshard-Carter, Cristina Naceur-Lombardelli, Andrew J Rowan, Selvaraju Veeriah, Kevin Litchfield, Philip A J Crosbie, Caroline Dive, Sergio A Quezada, Samuel M Janes, Mariam Jamal-Hanjani, Teresa Marafioti, null null, Nicholas McGranahan, Charles Swanton
Representation of genomic intratumor heterogeneity in multi-region non-small cell lung cancer patient-derived xenograft models. Nature communications 15 (1) (2024)
Hugh O'Brien, Max Salm, Laura T Morton, Maciej J Szukszto, Felix O'Farrell, Charlotte Boulton, Pablo D Becker, Yardena Sameuls, Charles Swanton, Marc R Mansour, Sine Reker Hadrup, Sergio A Quezada
Author Correction: Breaking the performance ceiling for neoantigen immunogenicity prediction. Nature cancer (2024)
Adrienne A Boire, Katy Burke, Thomas R Cox, Theresa Guise, Mariam Jamal-Hanjani, Tobias Janowitz, Rosandra Kaplan, Rebecca Jane Lee, Charles Swanton, Matthew G Vander Heiden, Erik Sahai
Why do patients with cancer die? Nature reviews. Cancer 24 (8) (2024)
Alastair Magness, Emma C Colliver, Katey S S Enfield, Claudia S Y Lee, Masako Shimato, Emer Daly, David Allan Moore, Monica Sivakumar, Karishma Valand, Dina Levi, Crispin T Hiley, Philip S Hobson, Febe van Maldegem, James L Reading, Sergio A Quezada, Julian Downward, Erik Sahai, Charles Swanton, Mihaela Angelova
Deep cell phenotyping and spatial analysis of multiplexed imaging with TRACERx-PHLEX. Nature communications 15 (1) (2024)
William Hill, Clare E Weeden, Charles Swanton
Tumor Promoters and Opportunities for Molecular Cancer Prevention. Cancer discovery 14 (7) (2024)
Xiaoxi Pan, Khalid AbdulJabbar, Jose Coelho-Lima, Anca-Ioana Grapa, Hanyun Zhang, Alvin Ho-Kwan Cheung, Juvenal Baena, Takahiro Karasaki, Claire Rachel Wilson, Marco Sereno, Selvaraju Veeriah, Sarah J Aitken, Allan Hackshaw, Andrew G Nicholson, Mariam Jamal-Hanjani, null null, Charles Swanton, Yinyin Yuan, John P C Le Quesne, David Allan Moore
The artificial intelligence-based model ANORAK improves histopathological grading of lung adenocarcinoma. Nature cancer (2024)
Sebastijan Hobor, Maise Al Bakir, Crispin T Hiley, Marcin Skrzypski, Alexander M Frankell, Bjorn Bakker, Thomas B K Watkins, Aleksandra Markovets, Jonathan R Dry, Andrew P Brown, Jasper van der Aart, Hilda van den Bos, Diana Carolina Johanna Spierings, Dahmane Oukrif, Marco Novelli, Turja Chakrabarti, Adam H Rabinowitz, Laila Ait Hassou, Saskia Litière, D Lucas Kerr, Lisa Tan, Gavin P Kelly, David Allan Moore, Matthew J Renshaw, Subramanian Venkatesan, William Hill, Ariana Huebner, Carlos Martínez-Ruiz, James R M Black, Wei Wu, Mihaela Angelova, Nicholas McGranahan, Julian Downward, Juliann Chmielecki, Carl Barrett, Kevin Litchfield, Su Kit Chew, Collin M Blakely, Elza C de Bruin, Floris Foijer, Karen H Vousden, Trever G Bivona, null null, Robert Edward Hynds, Nnennaya Kanu, Simone Zaccaria, Eva Grönroos, Charles Swanton
Mixed responses to targeted therapy driven by chromosomal instability through p53 dysfunction and genome doubling. Nature communications 15 (1) (2024)
Sebastijan Hobor, Maise Al Bakir, Crispin T Hiley, Marcin Skrzypski, Alexander M Frankell, Bjorn Bakker, Thomas B K Watkins, Aleksandra Markovets, Jonathan R Dry, Andrew P Brown, Jasper van der Aart, Hilda van den Bos, Diana Carolina Johanna Spierings, Dahmane Oukrif, Marco Novelli, Turja Chakrabarti, Adam H Rabinowitz, Laila Ait Hassou, Saskia Litière, D Lucas Kerr, Lisa Tan, Gavin P Kelly, David Allan Moore, Matthew J Renshaw, Subramanian Venkatesan, William Hill, Ariana Huebner, Carlos Martínez-Ruiz, James R M Black, Wei Wu, Mihaela Angelova, Nicholas McGranahan, Julian Downward, Juliann Chmielecki, Carl Barrett, Kevin Litchfield, Su Kit Chew, Collin M Blakely, Elza C de Bruin, Floris Foijer, Karen H Vousden, Trever G Bivona, null null, Robert Edward Hynds, Nnennaya Kanu, Simone Zaccaria, Eva Grönroos, Charles Swanton
Mixed responses to targeted therapy driven by chromosomal instability through p53 dysfunction and genome doubling. Nature communications 15 (1) (2024)
Katey S S Enfield, Emma C Colliver, Claudia S Y Lee, Alastair Magness, David Allan Moore, Monica Sivakumar, Kristiana Grigoriadis, Oriol Pich, Takahiro Karasaki, Philip S Hobson, Dina Levi, Selvaraju Veeriah, Clare Puttick, Emma L Nye, Mary Green, Krijn K Dijkstra, Masako Shimato, Ayse U Akarca, Teresa Marafioti, Roberto Salgado, Allan Hackshaw, null null, Mariam Jamal-Hanjani, Febe van Maldegem, Nicholas McGranahan, Benjamin Glass, Hanna Pulaski, Eric Walk, James L Reading, Sergio A Quezada, Crispin T Hiley, Julian Downward, Erik Sahai, Charles Swanton, Mihaela Angelova
Spatial Architecture of Myeloid and T Cells Orchestrates Immune Evasion and Clinical Outcome in Lung Cancer. Cancer discovery 14 (6) (2024)
Adrienne A Boire, Katy Burke, Thomas R Cox, Theresa Guise, Mariam Jamal-Hanjani, Tobias Janowitz, Rosandra Kaplan, Rebecca Jane Lee, Charles Swanton, Matthew G Vander Heiden, Erik Sahai
Why do patients with cancer die? Nature reviews. Cancer 24 (8) (2024)
Xiaoxi Pan, Khalid AbdulJabbar, Jose Coelho-Lima, Anca-Ioana Grapa, Hanyun Zhang, Alvin Ho-Kwan Cheung, Juvenal Baena, Takahiro Karasaki, Claire Rachel Wilson, Marco Sereno, Selvaraju Veeriah, Sarah J Aitken, Allan Hackshaw, Andrew G Nicholson, Mariam Jamal-Hanjani, null null, Charles Swanton, Yinyin Yuan, John P C Le Quesne, David Allan Moore
The artificial intelligence-based model ANORAK improves histopathological grading of lung adenocarcinoma. Nature cancer 5 (2) (2024)
Adrienne A Boire, Katy Burke, Thomas R Cox, Theresa Guise, Mariam Jamal-Hanjani, Tobias Janowitz, Rosandra Kaplan, Rebecca Jane Lee, Charles Swanton, Matthew G Vander Heiden, Erik Sahai
Why do patients with cancer die? Nature reviews. Cancer (2024)
Katey S S Enfield, Emma C Colliver, Claudia S Y Lee, Alastair Magness, David Allan Moore, Monica Sivakumar, Kristiana Grigoriadis, Oriol Pich, Takahiro Karasaki, Philip S Hobson, Dina Levi, Selvaraju Veeriah, Clare Puttick, Emma L Nye, Mary Green, Krijn K Dijkstra, Masako Shimato, Ayse U Akarca, Teresa Marafioti, Roberto Salgado, Allan Hackshaw, null null, Mariam Jamal-Hanjani, Febe van Maldegem, Nicholas McGranahan, Benjamin Glass, Hanna Pulaski, Eric Walk, James L Reading, Sergio A Quezada, Crispin T Hiley, Julian Downward, Erik Sahai, Charles Swanton, Mihaela Angelova
Spatial Architecture of Myeloid and T Cells Orchestrates Immune Evasion and Clinical Outcome in Lung Cancer. Cancer discovery 14 (6) (2024)
Alexander M Frankell, Michelle Dietzen, Maise Al Bakir, Emilia L Lim, Takahiro Karasaki, Sophia Ward, Selvaraju Veeriah, Emma C Colliver, Ariana Huebner, Abigail Bunkum, Mark S Hill, Kristiana Grigoriadis, David Allan Moore, James R M Black, Wing Kin Liu, Kerstin Thol, Oriol Pich, Thomas B K Watkins, Cristina Naceur-Lombardelli, Daniel E Cook, Roberto Salgado, Gareth A Wilson, Chris Bailey, Mihaela Angelova, Robert Bentham, Carlos Martínez-Ruiz, Christopher Abbosh, Andrew G Nicholson, John P C Le Quesne, Dhruva Biswas, Rachel Rosenthal, Clare Puttick, Sonya Hessey, Claudia S Y Lee, Paulina Prymas, Antonia Toncheva, Jon Smith, Wei Xing, Jérôme Nicod, Gillian Price, Keith M Kerr, Babu Naidu, Gary M Middleton, Kevin G Blyth, Dean A Fennell, Martin D Forster, Siow Ming Lee, Mary Falzon, Madeleine Hewish, Michael J Shackcloth, Eric Lim, Sarah Benafif, Peter Russell, Ekaterini Boleti, Matthew G Krebs, Jason F Lester, Dionysis Papadatos-Pastos, Tanya Ahmad, Ricky M Thakrar, David Lawrence, Neal Navani, Sam M Janes, Caroline Dive, Fiona H Blackhall, Yvonne Summers, Judith Cave, Teresa Marafioti, Javier Herrero, Sergio A Quezada, Karl S Peggs, Roland F Schwarz, Peter Van Loo, Daniël M Miedema, Nicolai Juul Birkbak, Crispin T Hiley, Allan Hackshaw, Simone Zaccaria, null null, Mariam Jamal-Hanjani, Nicholas McGranahan, Charles Swanton
Author Correction: The evolution of lung cancer and impact of subclonal selection in TRACERx. Nature (2024)
Adrienne A Boire, Katy Burke, Thomas R Cox, Theresa Guise, Mariam Jamal-Hanjani, Tobias Janowitz, Rosandra Kaplan, Rebecca Jane Lee, Charles Swanton, Matthew G Vander Heiden, Erik Sahai
Why do patients with cancer die? Nature reviews. Cancer 24 (8) (2024)
Helena Coggan, Clare E Weeden, Philip Pearce, Mohit P Dalwadi, Alastair Magness, Charles Swanton, Karen M Page
An agent-based modelling framework to study growth mechanisms in EGFR-L858R mutant cell alveolar type II cells. Royal Society open science 11 (7) (2024)
Michelle Dietzen, Haoran Zhai, Olivia Lucas, Oriol Pich, Christopher Barrington, Wei-Ting Lu, Sophia Ward, Yanping Guo, Robert Edward Hynds, Simone Zaccaria, Charles Swanton, Nicholas McGranahan, Nnennaya Kanu
Replication timing alterations are associated with mutation acquisition during breast and lung cancer evolution. Nature communications 15 (1) (2024)
Xiaoxi Pan, Khalid AbdulJabbar, Jose Coelho-Lima, Anca-Ioana Grapa, Hanyun Zhang, Alvin Ho-Kwan Cheung, Juvenal Baena, Takahiro Karasaki, Claire Rachel Wilson, Marco Sereno, Selvaraju Veeriah, Sarah J Aitken, Allan Hackshaw, Andrew G Nicholson, Mariam Jamal-Hanjani, null null, Charles Swanton, Yinyin Yuan, John P C Le Quesne, David Allan Moore
The artificial intelligence-based model ANORAK improves histopathological grading of lung adenocarcinoma. Nature cancer 5 (2) (2024)
Katey S S Enfield, Emma C Colliver, Claudia S Y Lee, Alastair Magness, David Allan Moore, Monica Sivakumar, Kristiana Grigoriadis, Oriol Pich, Takahiro Karasaki, Philip S Hobson, Dina Levi, Selvaraju Veeriah, Clare Puttick, Emma L Nye, Mary Green, Krijn K Dijkstra, Masako Shimato, Ayse U Akarca, Teresa Marafioti, Roberto Salgado, Allan Hackshaw, null null, Mariam Jamal-Hanjani, Febe van Maldegem, Nicholas McGranahan, Benjamin Glass, Hanna Pulaski, Eric Walk, James L Reading, Sergio A Quezada, Crispin T Hiley, Julian Downward, Erik Sahai, Charles Swanton, Mihaela Angelova
Spatial Architecture of Myeloid and T Cells Orchestrates Immune Evasion and Clinical Outcome in Lung Cancer. Cancer discovery 14 (6) (2024)
Michelle Dietzen, Haoran Zhai, Olivia Lucas, Oriol Pich, Christopher Barrington, Wei-Ting Lu, Sophia Ward, Yanping Guo, Robert Edward Hynds, Simone Zaccaria, Charles Swanton, Nicholas McGranahan, Nnennaya Kanu
Replication timing alterations are associated with mutation acquisition during breast and lung cancer evolution. Nature communications 15 (1) (2024)
Sebastijan Hobor, Maise Al Bakir, Crispin T Hiley, Marcin Skrzypski, Alexander M Frankell, Bjorn Bakker, Thomas B K Watkins, Aleksandra Markovets, Jonathan R Dry, Andrew P Brown, Jasper van der Aart, Hilda van den Bos, Diana Carolina Johanna Spierings, Dahmane Oukrif, Marco Novelli, Turja Chakrabarti, Adam H Rabinowitz, Laila Ait Hassou, Saskia Litière, D Lucas Kerr, Lisa Tan, Gavin P Kelly, David Allan Moore, Matthew J Renshaw, Subramanian Venkatesan, William Hill, Ariana Huebner, Carlos Martínez-Ruiz, James R M Black, Wei Wu, Mihaela Angelova, Nicholas McGranahan, Julian Downward, Juliann Chmielecki, Carl Barrett, Kevin Litchfield, Su Kit Chew, Collin M Blakely, Elza C de Bruin, Floris Foijer, Karen H Vousden, Trever G Bivona, null null, Robert Edward Hynds, Nnennaya Kanu, Simone Zaccaria, Eva Grönroos, Charles Swanton
Mixed responses to targeted therapy driven by chromosomal instability through p53 dysfunction and genome doubling. Nature communications 15 (1) (2024)
Toby M Baker, Siqi Lai, Andrew R Lynch, Tom Lesluyes, Haixi Yan, Huw A Ogilvie, Annelien Verfaillie, Stefan C Dentro, Amy L Bowes, Nischalan Pillay, Adrienne M Flanagan, Charles Swanton, Paul T Spellman, Maxime Tarabichi, Peter Van Loo
The history of chromosomal instability in genome doubled tumors. Cancer discovery (2024)
Alastair Magness, Emma C Colliver, Katey S S Enfield, Claudia S Y Lee, Masako Shimato, Emer Daly, David Allan Moore, Monica Sivakumar, Karishma Valand, Dina Levi, Crispin T Hiley, Philip S Hobson, Febe van Maldegem, James L Reading, Sergio A Quezada, Julian Downward, Erik Sahai, Charles Swanton, Mihaela Angelova
Deep cell phenotyping and spatial analysis of multiplexed imaging with TRACERx-PHLEX. Nature communications 15 (1) (2024)
Adrienne A Boire, Katy Burke, Thomas R Cox, Theresa Guise, Mariam Jamal-Hanjani, Tobias Janowitz, Rosandra Kaplan, Rebecca Jane Lee, Charles Swanton, Matthew G Vander Heiden, Erik Sahai
Why do patients with cancer die? Nature reviews. Cancer 24 (8) (2024)
Sebastijan Hobor, Maise Al Bakir, Crispin T Hiley, Marcin Skrzypski, Alexander M Frankell, Bjorn Bakker, Thomas B K Watkins, Aleksandra Markovets, Jonathan R Dry, Andrew P Brown, Jasper van der Aart, Hilda van den Bos, Diana Carolina Johanna Spierings, Dahmane Oukrif, Marco Novelli, Turja Chakrabarti, Adam H Rabinowitz, Laila Ait Hassou, Saskia Litière, D Lucas Kerr, Lisa Tan, Gavin P Kelly, David Allan Moore, Matthew J Renshaw, Subramanian Venkatesan, William Hill, Ariana Huebner, Carlos Martínez-Ruiz, James R M Black, Wei Wu, Mihaela Angelova, Nicholas McGranahan, Julian Downward, Juliann Chmielecki, Carl Barrett, Kevin Litchfield, Su Kit Chew, Collin M Blakely, Elza C de Bruin, Floris Foijer, Karen H Vousden, Trever G Bivona, null null, Robert Edward Hynds, Nnennaya Kanu, Simone Zaccaria, Eva Grönroos, Charles Swanton
Mixed responses to targeted therapy driven by chromosomal instability through p53 dysfunction and genome doubling. Nature communications 15 (1) (2024)
William Hill, Clare E Weeden, Charles Swanton
Tumor Promoters and Opportunities for Molecular Cancer Prevention. Cancer discovery 14 (7) (2024)
William Hill, Clare E Weeden, Charles Swanton
Tumor Promoters and Opportunities for Molecular Cancer Prevention. Cancer discovery (2024)
Katey S S Enfield, Emma C Colliver, Claudia S Y Lee, Alastair Magness, David Allan Moore, Monica Sivakumar, Kristiana Grigoriadis, Oriol Pich, Takahiro Karasaki, Philip S Hobson, Dina Levi, Selvaraju Veeriah, Clare Puttick, Emma L Nye, Mary Green, Krijn K Dijkstra, Masako Shimato, Ayse U Akarca, Teresa Marafioti, Roberto Salgado, Allan Hackshaw, TRACERx Consortium, Mariam Jamal-Hanjani, Febe van Maldegem, Nicholas McGranahan, Benjamin Glass, Hanna Pulaski, Eric Walk, James L Reading, Sergio A Quezada, Crispin T Hiley, Julian Downward, Erik Sahai, Charles Swanton, Mihaela Angelova
Spatial Architecture of Myeloid and T Cells Orchestrates Immune Evasion and Clinical Outcome in Lung Cancer. Cancer discovery (2024)
Xiaoxi Pan, Khalid AbdulJabbar, Jose Coelho-Lima, Anca-Ioana Grapa, Hanyun Zhang, Alvin Ho-Kwan Cheung, Juvenal Baena, Takahiro Karasaki, Claire Rachel Wilson, Marco Sereno, Selvaraju Veeriah, Sarah J Aitken, Allan Hackshaw, Andrew G Nicholson, Mariam Jamal-Hanjani, null null, Charles Swanton, Yinyin Yuan, John P C Le Quesne, David Allan Moore
The artificial intelligence-based model ANORAK improves histopathological grading of lung adenocarcinoma. Nature cancer 5 (2) (2024)
Adrienne A Boire, Katy Burke, Thomas R Cox, Theresa Guise, Mariam Jamal-Hanjani, Tobias Janowitz, Rosandra Kaplan, Rebecca Jane Lee, Charles Swanton, Matthew G Vander Heiden, Erik Sahai
Why do patients with cancer die? Nature reviews. Cancer 24 (8) (2024)
Xiaoxi Pan, Khalid AbdulJabbar, Jose Coelho-Lima, Anca-Ioana Grapa, Hanyun Zhang, Alvin Ho-Kwan Cheung, Juvenal Baena, Takahiro Karasaki, Claire Rachel Wilson, Marco Sereno, Selvaraju Veeriah, Sarah J Aitken, Allan Hackshaw, Andrew G Nicholson, Mariam Jamal-Hanjani, null null, Charles Swanton, Yinyin Yuan, John P C Le Quesne, David Allan Moore
The artificial intelligence-based model ANORAK improves histopathological grading of lung adenocarcinoma. Nature cancer (2024)
Xiaoxi Pan, Khalid AbdulJabbar, Jose Coelho-Lima, Anca-Ioana Grapa, Hanyun Zhang, Alvin Ho-Kwan Cheung, Juvenal Baena, Takahiro Karasaki, Claire Rachel Wilson, Marco Sereno, Selvaraju Veeriah, Sarah J Aitken, Allan Hackshaw, Andrew G Nicholson, Mariam Jamal-Hanjani, null null, Charles Swanton, Yinyin Yuan, John P C Le Quesne, David Allan Moore
The artificial intelligence-based model ANORAK improves histopathological grading of lung adenocarcinoma. Nature cancer 5 (2) (2024)
Katey S S Enfield, Emma C Colliver, Claudia S Y Lee, Alastair Magness, David Allan Moore, Monica Sivakumar, Kristiana Grigoriadis, Oriol Pich, Takahiro Karasaki, Philip S Hobson, Dina Levi, Selvaraju Veeriah, Clare Puttick, Emma L Nye, Mary Green, Krijn K Dijkstra, Masako Shimato, Ayse U Akarca, Teresa Marafioti, Roberto Salgado, Allan Hackshaw, null null, Mariam Jamal-Hanjani, Febe van Maldegem, Nicholas McGranahan, Benjamin Glass, Hanna Pulaski, Eric Walk, James L Reading, Sergio A Quezada, Crispin T Hiley, Julian Downward, Erik Sahai, Charles Swanton, Mihaela Angelova
Spatial Architecture of Myeloid and T Cells Orchestrates Immune Evasion and Clinical Outcome in Lung Cancer. Cancer discovery 14 (6) (2024)
Adrienne A Boire, Katy Burke, Thomas R Cox, Theresa Guise, Mariam Jamal-Hanjani, Tobias Janowitz, Rosandra Kaplan, Rebecca Jane Lee, Charles Swanton, Matthew G Vander Heiden, Erik Sahai
Why do patients with cancer die? Nature reviews. Cancer (2024)
Helena Coggan, Clare E Weeden, Philip Pearce, Mohit P Dalwadi, Alastair Magness, Charles Swanton, Karen M Page
An agent-based modelling framework to study growth mechanisms in EGFR-L858R mutant cell alveolar type II cells. Royal Society open science 11 (7) (2024)
Adrienne A Boire, Katy Burke, Thomas R Cox, Theresa Guise, Mariam Jamal-Hanjani, Tobias Janowitz, Rosandra Kaplan, Rebecca Jane Lee, Charles Swanton, Matthew G Vander Heiden, Erik Sahai
Why do patients with cancer die? Nature reviews. Cancer 24 (8) (2024)
Robert Edward Hynds, Ariana Huebner, David R Pearce, Mark S Hill, Ayse U Akarca, David Allan Moore, Sophia Ward, Kate H C Gowers, Takahiro Karasaki, Maise Al Bakir, Gareth A Wilson, Oriol Pich, Carlos Martínez-Ruiz, A S Md Mukarram Hossain, Simon P Pearce, Monica Sivakumar, Assma Ben Aissa, Eva Grönroos, Deepak P Chandrasekharan, Krishna K Kolluri, Rebecca Towns, Kaiwen Wang, Daniel E Cook, Leticia Bosshard-Carter, Cristina Naceur-Lombardelli, Andrew J Rowan, Selvaraju Veeriah, Kevin Litchfield, Philip A J Crosbie, Caroline Dive, Sergio A Quezada, Samuel M Janes, Mariam Jamal-Hanjani, Teresa Marafioti, null null, Nicholas McGranahan, Charles Swanton
Representation of genomic intratumor heterogeneity in multi-region non-small cell lung cancer patient-derived xenograft models. Nature communications 15 (1) (2024)
Toby M Baker, Siqi Lai, Andrew R Lynch, Tom Lesluyes, Haixi Yan, Huw A Ogilvie, Annelien Verfaillie, Stefan C Dentro, Amy L Bowes, Nischalan Pillay, Adrienne M Flanagan, Charles Swanton, Paul T Spellman, Maxime Tarabichi, Peter Van Loo
The history of chromosomal instability in genome doubled tumors. Cancer discovery (2024)
Sebastijan Hobor, Maise Al Bakir, Crispin T Hiley, Marcin Skrzypski, Alexander M Frankell, Bjorn Bakker, Thomas B K Watkins, Aleksandra Markovets, Jonathan R Dry, Andrew P Brown, Jasper van der Aart, Hilda van den Bos, Diana Carolina Johanna Spierings, Dahmane Oukrif, Marco Novelli, Turja Chakrabarti, Adam H Rabinowitz, Laila Ait Hassou, Saskia Litière, D Lucas Kerr, Lisa Tan, Gavin P Kelly, David Allan Moore, Matthew J Renshaw, Subramanian Venkatesan, William Hill, Ariana Huebner, Carlos Martínez-Ruiz, James R M Black, Wei Wu, Mihaela Angelova, Nicholas McGranahan, Julian Downward, Juliann Chmielecki, Carl Barrett, Kevin Litchfield, Su Kit Chew, Collin M Blakely, Elza C de Bruin, Floris Foijer, Karen H Vousden, Trever G Bivona, null null, Robert Edward Hynds, Nnennaya Kanu, Simone Zaccaria, Eva Grönroos, Charles Swanton
Mixed responses to targeted therapy driven by chromosomal instability through p53 dysfunction and genome doubling. Nature communications 15 (1) (2024)
Xiaoxi Pan, Khalid AbdulJabbar, Jose Coelho-Lima, Anca-Ioana Grapa, Hanyun Zhang, Alvin Ho-Kwan Cheung, Juvenal Baena, Takahiro Karasaki, Claire Rachel Wilson, Marco Sereno, Selvaraju Veeriah, Sarah J Aitken, Allan Hackshaw, Andrew G Nicholson, Mariam Jamal-Hanjani, null null, Charles Swanton, Yinyin Yuan, John P C Le Quesne, David Allan Moore
The artificial intelligence-based model ANORAK improves histopathological grading of lung adenocarcinoma. Nature cancer 5 (2) (2024)
Maria Antonietta Cerone, Tara C Mills, Rowena Sharpe, David McBride, Moira MacDonald, Suzanne MacMahon, Hood Mugalaasi, Pauline Rehal, Alessandro Rettino, Helen Roberts, Mark Ross, Donald Edward White, John Peden, Janette Rawlinson, Steffan N Ho, Simon Hollingsworth, Sanjay Popat, Gary M Middleton, Peter Johnson, Charles Swanton, null null
Correction to: The Cancer Research UK Stratified Medicine Programme as a model for delivering personalised cancer care. British journal of cancer (2023)
Kevin W Ng, Jesse Boumelha, Katey S S Enfield, Jorge Almagro, Hongui Cha, Oriol Pich, Takahiro Karasaki, David A Moore, Roberto Salgado, Monica Sivakumar, George R Young, Miriam Molina-Arcas, Sophie de Carné Trécesson, Panayiotis Anastasiou, Annika Fendler, Lewis Au, Scott T C Shepherd, Carlos Martínez-Ruiz, Clare Puttick, James R M Black, Thomas B K Watkins, Hyemin Kim, Seohee Shim, Nikhil Faulkner, Jan Attig, Selvaraju Veeriah, Neil Magno, Sophia Ward, Alexander M Frankell, Maise Al Bakir, Emilia L Lim, Mark S Hill, Gareth A Wilson, Daniel E Cook, Nicolai Juul Birkbak, Axel Behrens, Nadia Yousaf, Sanjay Popat, Allan Hackshaw, null null, null null, Crispin T Hiley, Kevin Litchfield, Nicholas McGranahan, Mariam Jamal-Hanjani, James Larkin, Se-Hoon Lee, Samra Turajlic, Charles Swanton, Julian Downward, George Kassiotis
Antibodies against endogenous retroviruses promote lung cancer immunotherapy. Nature (2023)
Carlos Martínez-Ruiz, James R M Black, Clare Puttick, Mark S Hill, Jonas Demeulemeester, Elizabeth Larose Cadieux, Kerstin Thol, Thomas P Jones, Selvaraju Veeriah, Cristina Naceur-Lombardelli, Antonia Toncheva, Paulina Prymas, Andrew Rowan, Sophia Ward, Laura Cubitt, Foteini Athanasopoulou, Oriol Pich, Takahiro Karasaki, David Allan Moore, Roberto Salgado, Emma C Colliver, Carla Castignani, Michelle Dietzen, Ariana Huebner, Maise Al Bakir, Miljana Tanić, Thomas B K Watkins, Emilia L Lim, Ali M Al-Rashed, Danny Lang, James Clements, Daniel E Cook, Rachel Rosenthal, Gareth A Wilson, Alexander M Frankell, Sophie de Carné Trécesson, Philip East, Nnennaya Kanu, Kevin Litchfield, Nicolai Juul Birkbak, Allan Hackshaw, Stephan Beck, Peter Van Loo, Mariam Jamal-Hanjani, null null, Charles Swanton, Nicholas McGranahan
Genomic-transcriptomic evolution in lung cancer and metastasis. Nature (2023)
Lavinia Spain, Alexander Coulton, Irene Lobon, Andrew Rowan, Desiree Schnidrig, Scott T C Shepherd, Benjamin Shum, Fiona Byrne, Maria Goicoechea, Elisa Piperni, Lewis Au, Kim Edmonds, Eleanor Carlyle, Nikki Hunter, Alexandra Renn, Christina Messiou, Peta Hughes, Jaime Nobbs, Floris Foijer, Hilda van den Bos, Rene Wardenaar, Diana Carolina Johanna Spierings, Charlotte Spencer, Andreas Michael Schmitt, Zayd Tippu, Karla Lingard, Lauren Grostate, Kema Peat, Kayleigh Kelly, Sarah Sarker, Sarah Vaughan, Mary Mangwende, Lauren Terry, Denise Kelly, Jennifer Biano, Aida Murra, Justine Korteweg, Charlotte Lewis, Molly OFlaherty, Anne-Laure Cattin, Max Emmerich, Camille L Gerard, Husayn Ahmed Pallikonda, Joanna Lynch, Robert Mason, Aljosja Rogiers, Hang Xu, Ariana Huebner, Nicholas McGranahan, Maise Al Bakir, Jun Murai, Cristina Naceur-Lombardelli, Elaine Borg, Miriam Mitchison, David Allan Moore, Mary Falzon, Ian Proctor, Gordon W H Stamp, Emma L Nye, Kate Young, Andrew J S Furness, Lisa M Pickering, Ruby Stewart, Ula Mahadeva, Anna C Green, James M G Larkin, Kevin Litchfield, Charles Swanton, Mariam Jamal-Hanjani, Samra Turajlic
Late-stage metastatic melanoma emerges through a diversity of evolutionary pathways. Cancer discovery (2023)
Deborah R Caswell, Charles Swanton
Distinct Mutagenic Activity of APOBEC3G Cytidine Deaminase Identified in Bladder Cancer. Cancer research 83 (4) (2023)
A M Mahedi Hasan, Paolo Cremaschi, Daniel Wetterskog, Anuradha Jayaram, Stephen Q Wong, Scott Williams, Anupama Pasam, Anna Sofia Trigos, Blanca Trujillo, Emily Grist, Stefanie Friedrich, Osvaldas Vainauskas, Marina Parry, Mazlina Ismail, Wout Devlies, Anna Wingate, Mark Linch, Cristina Naceur-Lombardelli, null null, Charles Swanton, Mariam Jamal-Hanjani, Stefano Lise, Shahneen Sandhu, Gerhardt Attard
Copy number architectures define treatment-mediated selection of lethal prostate cancer clones. Nature communications 14 (1) (2023)
James L Reading, Deborah R Caswell, Charles Swanton
Tumor heterogeneity impairs immunogenicity in mismatch repair deficient tumors. Nature genetics (2023)
Hugh O'Brien, Max Salm, Laura Morton, Maciej J Szukszto, Felix O'Farrell, Charlotte Boulton, Pablo D Becker, Yardena Sameuls, Charles Swanton, Marc R Mansour, Sine Reker Hadrup, Sergio A Quezada
Breaking the performance ceiling for neoantigen immunogenicity prediction. Nature cancer 4 (12) (2023)
Christopher Abbosh, Alexander M Frankell, Thomas Harrison, Judit Kisistok, Aaron Garnett, Laura Johnson, Selvaraju Veeriah, Mike Moreau, Adrian Chesh, Tafadzwa L Chaunzwa, Jakob Weiss, Morgan R Schroeder, Sophia Ward, Kristiana Grigoriadis, Aamir Shahpurwalla, Kevin Litchfield, Clare Puttick, Dhruva Biswas, Takahiro Karasaki, James R M Black, Carlos Martínez-Ruiz, Maise Al Bakir, Oriol Pich, Thomas B K Watkins, Emilia L Lim, Ariana Huebner, David Allan Moore, Nadia Godin-Heymann, Anne L'Hernault, Hannah Bye, Aaron Odell, Paula Roberts, Fabio Gomes, Akshay J Patel, Elizabeth Manzano, Crispin T Hiley, Nicolas Carey, Joan Riley, Daniel E Cook, Darren Hodgson, Daniel Stetson, J Carl Barrett, Roderik M Kortlever, Gerard I Evan, Allan Hackshaw, Robert D Daber, Jacqueline A Shaw, Hugo J W L Aerts, Abel Licon, Josh Stahl, Mariam Jamal-Hanjani, null null, Nicolai Juul Birkbak, Nicholas McGranahan, Charles Swanton
Tracking early lung cancer metastatic dissemination in TRACERx using ctDNA. Nature (2023)
Hugh O'Brien, Max Salm, Laura T Morton, Maciej J Szukszto, Felix O'Farrell, Charlotte Boulton, Pablo D Becker, Yardena Sameuls, Charles Swanton, Marc R Mansour, Sine Reker Hadrup, Sergio A Quezada
Breaking the performance ceiling for neoantigen immunogenicity prediction. Nature cancer 4 (12) (2023)
Maria Antonietta Cerone, Tara C Mills, Rowena Sharpe, David McBride, Moira MacDonald, Suzanne MacMahon, Hood Mugalaasi, Pauline Rehal, Alessandro Rettino, Helen Roberts, Mark Ross, Donald Edward White, John Peden, Janette Rawlinson, Steffan N Ho, Simon Hollingsworth, Sanjay Popat, Gary M Middleton, Peter Johnson, Charles Swanton, null null
The Cancer Research UK Stratified Medicine Programme as a model for delivering personalised cancer care. British journal of cancer 128 (2) (2023)
Takahiro Karasaki, David Allan Moore, Selvaraju Veeriah, Cristina Naceur-Lombardelli, Antonia Toncheva, Neil Magno, Sophia Ward, Maise Al Bakir, Thomas B K Watkins, Kristiana Grigoriadis, Ariana Huebner, Mark S Hill, Alexander M Frankell, Christopher Abbosh, Clare Puttick, Haoran Zhai, Francisco Gimeno-Valiente, Sadegh Saghafinia, Nnennaya Kanu, Michelle Dietzen, Oriol Pich, Emilia L Lim, Carlos Martínez-Ruiz, James R M Black, Dhruva Biswas, Brittany B Campbell, Claudia S Y Lee, Emma C Colliver, Katey S S Enfield, Sonya Hessey, Crispin T Hiley, Simone Zaccaria, Kevin Litchfield, Nicolai Juul Birkbak, Elizabeth Larose Cadieux, Jonas Demeulemeester, Peter Van Loo, Prasad S Adusumilli, Kay See Tan, Waseem Cheema, Francisco Sanchez-Vega, David R Jones, Natasha Rekhtman, William D Travis, Allan Hackshaw, Teresa Marafioti, Roberto Salgado, John P C Le Quesne, Andrew G Nicholson, null null, Nicholas McGranahan, Charles Swanton, Mariam Jamal-Hanjani
Evolutionary characterization of lung adenocarcinoma morphology in TRACERx. Nature medicine (2023)
Maria Antonietta Cerone, Tara C Mills, Rowena Sharpe, David McBride, Moira MacDonald, Suzanne MacMahon, Hood Mugalaasi, Pauline Rehal, Alessandro Rettino, Helen Roberts, Mark Ross, Donald Edward White, John Peden, Janette Rawlinson, Steffan N Ho, Simon Hollingsworth, Sanjay Popat, Gary M Middleton, Peter Johnson, Charles Swanton, null null
Correction to: The Cancer Research UK Stratified Medicine Programme as a model for delivering personalised cancer care. British journal of cancer (2023)
Maria Antonietta Cerone, Tara C Mills, Rowena Sharpe, David McBride, Moira MacDonald, Suzanne MacMahon, Hood Mugalaasi, Pauline Rehal, Alessandro Rettino, Helen Roberts, Mark Ross, Donald Edward White, John Peden, Janette Rawlinson, Steffan N Ho, Simon Hollingsworth, Sanjay Popat, Gary M Middleton, Peter Johnson, Charles Swanton, null null
The Cancer Research UK Stratified Medicine Programme as a model for delivering personalised cancer care. British journal of cancer 128 (2) (2023)
Aaron Javitt, Merav D Shmueli, Matthias P Kramer, Aleksandra A Kolodziejczyk, Ivan J Cohen, Lihi Radomir, Daoud Sheban, Iris Kamer, Kevin Litchfield, Elizabeta Bab-Dinitz, Oranit Zadok, Vanessa Neiens, Adi Ulman, Hila Wolf-Levy, Avital Eisenberg-Lerner, Assaf Kacen, Michal Alon, Ana Toste Rêgo, Elvira Stacher-Priehse, Michael Lindner, Ina Koch, Jair Bar, Charles Swanton, Yardena Sameuls, Yishai Levin, Paula C A da Fonseca, Eran Elinav, Nir Friedman, Silke Meiners, Yifat Merbl
The proteasome regulator PSME4 modulates proteasome activity and antigen diversity to abrogate antitumor immunity in NSCLC. Nature cancer (2023)
Maria Antonietta Cerone, Tara C Mills, Rowena Sharpe, David McBride, Moira MacDonald, Suzanne MacMahon, Hood Mugalaasi, Pauline Rehal, Alessandro Rettino, Helen Roberts, Mark Ross, Donald Edward White, John Peden, Janette Rawlinson, Steffan N Ho, Simon Hollingsworth, Sanjay Popat, Gary M Middleton, Peter Johnson, Charles Swanton, null null
The Cancer Research UK Stratified Medicine Programme as a model for delivering personalised cancer care. British journal of cancer 128 (2) (2023)
Kristiana Grigoriadis, Ariana Huebner, Abigail Bunkum, Emma C Colliver, Alexander M Frankell, Mark S Hill, Kerstin Thol, Nicolai Juul Birkbak, Charles Swanton, Simone Zaccaria, Nicholas McGranahan
CONIPHER: a computational framework for scalable phylogenetic reconstruction with error correction. Nature protocols (2023)
Yanshuo Chu, Enyu Dai, Yating Li, Guangchun Han, Guangsheng Pei, Davis R Ingram, Krupa Thakkar, Jiang-Jiang Qin, Minghao Dang, Xiuning Li, Can Hu, Qing Deng, Ansam Sinjab, Pravesh Gupta, Ruiping Wang, Dapeng Hao, Fuduan Peng, Xinmiao Yan, Yunhe Liu, Shumei Song, Shaojun Zhang, John Victor Heymach, Alexandre Reuben, Yasir Y Elamin, Melissa P Pizzi, Yang Lu, Rossana Lazcano, Jian Hu, Mingyao Li, Michael A Curran, P Andrew Futreal, Anirban Maitra, Amir A Jazaeri, Jaffer A Ajani, Charles Swanton, Xiang-Dong Cheng, Hussein A Abbas, Maura Gillison, Krishna P Bhat, Alexander J F Lazar, Michael R Green, Kevin Litchfield, Humam Kadara, Cassian Yee, Linghua Wang
Pan-cancer T cell atlas links a cellular stress response state to immunotherapy resistance. Nature medicine (2023)
Deborah R Caswell, Charles Swanton
Distinct Mutagenic Activity of APOBEC3G Cytidine Deaminase Identified in Bladder Cancer. Cancer research 83 (4) (2023)
Alexander M Frankell, Michelle Dietzen, Maise Al Bakir, Emilia L Lim, Takahiro Karasaki, Sophia Ward, Selvaraju Veeriah, Emma C Colliver, Ariana Huebner, Abigail Bunkum, Mark S Hill, Kristiana Grigoriadis, David Allan Moore, James R M Black, Wing Kin Liu, Kerstin Thol, Oriol Pich, Thomas B K Watkins, Cristina Naceur-Lombardelli, Daniel E Cook, Roberto Salgado, Gareth A Wilson, Chris Bailey, Mihaela Angelova, Robert Bentham, Carlos Martínez-Ruiz, Christopher Abbosh, Andrew G Nicholson, John P C Le Quesne, Dhruva Biswas, Rachel Rosenthal, Clare Puttick, Sonya Hessey, Claudia S Y Lee, Paulina Prymas, Antonia Toncheva, Jon Smith, Wei Xing, Jérôme Nicod, Gillian Price, Keith M Kerr, Babu Naidu, Gary M Middleton, Kevin G Blyth, Dean A Fennell, Martin D Forster, Siow Ming Lee, Mary Falzon, Madeleine Hewish, Michael J Shackcloth, Eric Lim, Sarah Benafif, Peter Russell, Ekaterini Boleti, Matthew G Krebs, Jason F Lester, Dionysis Papadatos-Pastos, Tanya Ahmad, Ricky M Thakrar, David Lawrence, Neal Navani, Sam M Janes, Caroline Dive, Fiona H Blackhall, Yvonne Summers, Judith Cave, Teresa Marafioti, Javier Herrero, Sergio A Quezada, Karl S Peggs, Roland F Schwarz, Peter Van Loo, Daniël M Miedema, Nicolai Juul Birkbak, Crispin T Hiley, Allan Hackshaw, Simone Zaccaria, null null, Mariam Jamal-Hanjani, Nicholas McGranahan, Charles Swanton
The evolution of lung cancer and impact of subclonal selection in TRACERx. Nature (2023)
Hanyun Zhang, Khalid AbdulJabbar, David Allan Moore, Ayse U Akarca, Katey S S Enfield, Mariam Jamal-Hanjani, Shan E Ahmed Raza, Selvaraju Veeriah, Roberto Salgado, Nicholas McGranahan, John P C Le Quesne, Charles Swanton, Teresa Marafioti, Yinyin Yuan
Spatial positioning of immune hotspots reflects the interplay between B and T cells in lung squamous cell carcinoma. Cancer research (2023)
Hugh O'Brien, Max Salm, Laura Morton, Maciej J Szukszto, Felix O'Farrell, Charlotte Boulton, Pablo D Becker, Yardena Sameuls, Charles Swanton, Marc R Mansour, Sine Reker Hadrup, Sergio A Quezada
Breaking the performance ceiling for neoantigen immunogenicity prediction. Nature cancer 4 (12) (2023)
William Hill, Emilia L Lim, Clare E Weeden, Claudia S Y Lee, Marcellus Augustine, Kezhong Chen, Feng-Che Kuan, Fabio Marongiu, Edward J Evans, David Allan Moore, Felipe S Rodrigues, Oriol Pich, Bjorn Bakker, Hongui Cha, Renelle Myers, Febe van Maldegem, Jesse Boumelha, Selvaraju Veeriah, Andrew Rowan, Cristina Naceur-Lombardelli, Takahiro Karasaki, Monica Sivakumar, Swapnanil De, Deborah R Caswell, Ai Nagano, James R M Black, Carlos Martínez-Ruiz, Min Hyung Ryu, Ryan D Huff, Shijia Li, Marie-Julie Favé, Alastair Magness, Alejandro Suarez-Bonnet, Simon Lawrence Priestnall, Margreet Lüchtenborg, Katrina Lavelle, Joanna Pethick, Steven Hardy, Fiona E McRonald, Meng-Hung Lin, Clara I Troccoli, Moumita Ghosh, York E Miller, Daniel T Merrick, Robert L Keith, Maise Al Bakir, Chris Bailey, Mark S Hill, Lao H Saal, Yilun Chen, Anthony M George, Christopher Abbosh, Nnennaya Kanu, Se-Hoon Lee, Nicholas McGranahan, Christine D Berg, Peter D Sasieni, Richard S Houlston, Clare Turnbull, Stephen Lam, Phillip Awadalla, Eva Grönroos, Julian Downward, Tyler Jacks, Christopher Carlsten, Ilaria Malanchi, Allan Hackshaw, Kevin Litchfield, null null, James DeGregori, Mariam Jamal-Hanjani, Charles Swanton
Lung adenocarcinoma promotion by air pollutants. Nature 616 (7955) (2023)
Hugh O'Brien, Max Salm, Laura Morton, Maciej J Szukszto, Felix O'Farrell, Charlotte Boulton, Pablo D Becker, Yardena Sameuls, Charles Swanton, Marc R Mansour, Sine Reker Hadrup, Sergio A Quezada
Breaking the performance ceiling for neoantigen immunogenicity prediction. Nature cancer (2023)
Maria Antonietta Cerone, Tara C Mills, Rowena Sharpe, David McBride, Moira MacDonald, Suzanne MacMahon, Hood Mugalaasi, Pauline Rehal, Alessandro Rettino, Helen Roberts, Mark Ross, Donald Edward White, John Peden, Janette Rawlinson, Steffan N Ho, Simon Hollingsworth, Sanjay Popat, Gary M Middleton, Peter Johnson, Charles Swanton, null null
The Cancer Research UK Stratified Medicine Programme as a model for delivering personalised cancer care. British journal of cancer 128 (2) (2023)
Maria Antonietta Cerone, Tara C Mills, Rowena Sharpe, David McBride, Moira MacDonald, Suzanne MacMahon, Hood Mugalaasi, Pauline Rehal, Alessandro Rettino, Helen Roberts, Mark Ross, Donald Edward White, John Peden, Janette Rawlings, Stephan N Ho, Simon Hollingsworth, Sanjay Popat, Gary M Middleton, Peter Johnson, Charles Swanton, null null
The Cancer Research UK Stratified Medicine Programme as a model for delivering personalised cancer care. British journal of cancer (2023)
Jayant K Rane, Alexander M Frankell, Clare E Weeden, Charles Swanton
Clonal evolution in healthy and premalignant tissues: implications for early cancer interception strategies. Cancer prevention research (Philadelphia, Pa.) (2023)
Hugh O'Brien, Max Salm, Laura Morton, Maciej J Szukszto, Felix O'Farrell, Charlotte Boulton, Pablo D Becker, Yardena Sameuls, Charles Swanton, Marc R Mansour, Sine Reker Hadrup, Sergio A Quezada
Breaking the performance ceiling for neoantigen immunogenicity prediction. Nature cancer 4 (12) (2023)
Osbert Zalay, Dennis Bontempi, Danielle S Bitterman, Nicolai Juul Birkbak, Derek Shyr, Fridolin Haugg, Jack M Qian, Hannah J Roberts, Subha Perni, Vasco Prudente, Suraj Pai, Andre Dekker, Benjamin Haibe-Kains, Christian Guthier, Tracy Balboni, Laura Warren, Monica Krishan, Benjamin H Kann, Charles Swanton, Dirk De Ruysscher, Raymond H Mak, Hugo J W L Aerts
Decoding biological age from face photographs using deep learning. medRxiv : the preprint server for health sciences (2023)
Deborah R Caswell, Philippe Gui, Manasi K Mayekar, Emily K Law, Oriol Pich, Chris Bailey, Jesse Boumelha, D Lucas Kerr, Collin M Blakely, Tadashi Manabe, Carlos Martinez-Ruiz, Bjorn Bakker, Juan De Dios Palomino Villcas, Natalie I Vokes, Michelle Dietzen, Mihaela Angelova, Beatrice Gini, Whitney Tamaki, Paul Allegakoen, Wei Wu, Timothy J Humpton, William Hill, Mona Tomaschko, Wei-Ting Lu, Franziska Haderk, Maise Al Bakir, Ai Nagano, Francisco Gimeno-Valiente, Sophie de Carné Trécesson, Roberto Vendramin, Vittorio Barbè, Miriam Mugabo, Clare E Weeden, Andrew Rowan, Caroline E McCoach, Bruna Almeida, Mary Green, Carlos Gomez, Shigeki Nanjo, Dora Barbosa, Chris Moore, Joanna Przewrocka, James R M Black, Eva Grönroos, Alejandro Suarez-Bonnet, Simon Lawrence Priestnall, Caroline Zverev, Scott Lighterness, James Cormack, Victor Olivas, Lauren Cech, Trisha Andrews, Brandon Rule, Yuwei Jiao, Xinzhu Zhang, Paul Ashford, Cameron Durfee, Subramanian Venkatesan, Nuri Alpay Temiz, Lisa Tan, Lindsay K Larson, Prokopios P Argyris, William L Brown, Elizabeth A Yu, Julia K Rotow, Udayan Guha, Nitin Roper, Johnny Yu, Rachel Isaksson Vogel, Nicholas J Thomas, Antonio Marra, Pier Selenica, Helena Alexandra Yu, Samuel F Bakhoum, Su Kit Chew, Jorge Sergio Reis-Filho, Mariam Jamal-Hanjani, Karen H Vousden, Nicholas McGranahan, Eliezer Van Allen, Nnennaya Kanu, Reuben Stewart Harris, Julian Downward, Trever G Bivona, Charles Swanton
The role of APOBEC3B in lung tumor evolution and targeted cancer therapy resistance. Nature genetics (2023)
Maria Antonietta Cerone, Tara C Mills, Rowena Sharpe, David McBride, Moira MacDonald, Suzanne MacMahon, Hood Mugalaasi, Pauline Rehal, Alessandro Rettino, Helen Roberts, Mark Ross, Donald Edward White, John Peden, Janette Rawlinson, Steffan N Ho, Simon Hollingsworth, Sanjay Popat, Gary M Middleton, Peter Johnson, Charles Swanton, null null
The Cancer Research UK Stratified Medicine Programme as a model for delivering personalised cancer care. British journal of cancer (2023)
Maria Antonietta Cerone, Tara C Mills, Rowena Sharpe, David McBride, Moira MacDonald, Suzanne MacMahon, Hood Mugalaasi, Pauline Rehal, Alessandro Rettino, Helen Roberts, Mark Ross, Donald Edward White, John Peden, Janette Rawlinson, Steffan N Ho, Simon Hollingsworth, Sanjay Popat, Gary M Middleton, Peter Johnson, Charles Swanton, null null
The Cancer Research UK Stratified Medicine Programme as a model for delivering personalised cancer care. British journal of cancer (2023)
Maise Al Bakir, Ariana Huebner, Carlos Martínez-Ruiz, Kristiana Grigoriadis, Thomas B K Watkins, Oriol Pich, David Allan Moore, Selvaraju Veeriah, Sophia Ward, Joanne Laycock, Diana Johnson, Andrew Rowan, Maryam Razaq, Mita Akther, Cristina Naceur-Lombardelli, Paulina Prymas, Antonia Toncheva, Sonya Hessey, Michelle Dietzen, Emma C Colliver, Alexander M Frankell, Abigail Bunkum, Emilia L Lim, Takahiro Karasaki, Christopher Abbosh, Crispin T Hiley, Mark S Hill, Daniel E Cook, Gareth A Wilson, Roberto Salgado, Emma Nye, Richard Kevin Stone, Dean A Fennell, Gillian Price, Keith M Kerr, Babu Naidu, Gary M Middleton, Yvonne Summers, Colin R Lindsay, Fiona H Blackhall, Judith Cave, Kevin G Blyth, Arjun Nair, Asia Ahmed, Magali N Taylor, Alexander James Procter, Mary Falzon, David Lawrence, Neal Navani, Ricky M Thakrar, Samuel M Janes, Dionysis Papadatos-Pastos, Martin D Forster, Siow Ming Lee, Tanya Ahmad, Sergio A Quezada, Karl S Peggs, Peter Van Loo, Caroline Dive, Allan Hackshaw, Nicolai Juul Birkbak, Simone Zaccaria, null null, Mariam Jamal-Hanjani, Nicholas McGranahan, Charles Swanton
The evolution of non-small cell lung cancer metastases in TRACERx. Nature (2023)
Othman Al-Sawaf, Jakob Weiss, Marcin Skrzypski, Jie Min Lam, Takahiro Karasaki, Francisco Zambrana, Andrew C Kidd, Alexander M Frankell, Thomas B K Watkins, Carlos Martínez-Ruiz, Clare Puttick, James R M Black, Ariana Huebner, Maise Al Bakir, Mateo Sokač, Susie Collins, Selvaraju Veeriah, Neil Magno, Cristina Naceur-Lombardelli, Paulina Prymas, Antonia Toncheva, Sophia Ward, Nick Jayanth, Roberto Salgado, Christopher P Bridge, David Chistopher Christiani, Raymond H Mak, Camden Bay, Michael Rosenthal, Naveed Sattar, Paul I Welsh, Ying Liu, Norbert Perrimon, Karteek Popuri, Mirza Faisal Beg, Nicholas McGranahan, Allan Hackshaw, Danna M Breen, Stephen I O'Rahilly, Nicolai Juul Birkbak, Hugo J W L Aerts, null null, Mariam Jamal-Hanjani, Charles Swanton
Body composition and lung cancer-associated cachexia in TRACERx. Nature medicine (2023)
Peter D Sasieni, Rebecca Smittenaar, Earl Hubbell, John Broggio, Richard D Neal, Charles Swanton
Modelled mortality benefits of multi-cancer early detection screening in England. British journal of cancer (2023)
Timothy W Russell, Hermaleigh Townsley, Sam Abbott, Joel Hellewell, Edward J Carr, Nicholas G Davies, Rachael Pung, Billy J Quilty, David Hodgson, Ashley S Fowler, Lorin Adams, Christopher Bailey, Harriet V Mears, Ruth Harvey, Bobbi Clayton, Nicola O'Reilly, Yenting Ngai, Jérôme Nicod, Steven J Gamblin, Bryan Williams, Sonia Gandhi, Charles Swanton, Rupert C L Beale, David L V Bauer, Emma C Wall, Adam J Kucharski
Within-host SARS-CoV-2 viral kinetics informed by complex life course exposures reveals different intrinsic properties of Omicron and Delta variants. medRxiv : the preprint server for health sciences (2023)
Charles Swanton
Turning a failing PhD around. Nature cancer 4 (10) (2023)
Jesse Boumelha, Sophie de Carné Trécesson, Emily K Law, Pablo Romero-Clavijo, Matthew A Coelho, Kevin W Ng, Edurne Mugarza, Christopher Moore, Sareena Rana, Deborah R Caswell, Miguel Murillo, David C Hancock, Prokopios P Argyris, William L Brown, Cameron Durfee, Lindsay K Larson, Rachel Isaksson Vogel, Alejandro Suarez-Bonnet, Simon Lawrence Priestnall, Philip East, Sarah J Ross, George Kassiotis, Miriam Molina-Arcas, Charles Swanton, Reuben Stewart Harris, Julian Downward
An Immunogenic Model of KRAS-Mutant Lung Cancer Enables Evaluation of Targeted Therapy and Immunotherapy Combinations. Cancer research 82 (19) (2022)
Yin Wu, Dhruva Biswas, Ieva Usaite, Mihaela Angelova, Stefan Boeing, Takahiro Karasaki, Selvaraju Veeriah, Justyna Czyzewska-Khan, Cienne Morton, Magdalene Joseph, Sonya Hessey, James L Reading, Andrew Georgiou, Maise Al-Bakir, null null, Nicholas McGranahan, Mariam Jamal-Hanjani, Allan Hackshaw, Sergio A Quezada, Adrian C Hayday, Charles Swanton
A local human Vδ1 T cell population is associated with survival in nonsmall-cell lung cancer. Nature cancer 3 (6) (2022)
Kevin W Ng, Nikhil Faulkner, Katja Finsterbusch, Mary Y Wu, Ruth Harvey, Saira Hussain, Maria Greco, Yafei Liu, Svend Kjær, Charles Swanton, Sonia Gandhi, Rupert C L Beale, Steven J Gamblin, Peter Cherepanov, John W McCauley, Rodney S Daniels, Michael Howell, Hisashi Arase, Andreas Wack, David L V Bauer, George Kassiotis
SARS-CoV-2 S2-targeted vaccination elicits broadly neutralizing antibodies. Science translational medicine 14 (655) (2022)
Maryam Yousefi, Gábor Boross, Carly Weiss, Christopher W Murray, Jess D Hebert, Hongchen Cai, Emily L Ashkin, Saswati Karmakar, Laura Andrejka, Leo Chen, Minwei Wang, Min K Tsai, Wen-Yang Lin, Chuan Li, Pegah Yakhchalian, Caterina I Colón, Su-Kit Chew, Pauline Chu, Charles Swanton, Christian A Kunder, Dmitri A Petrov, Monte M Winslow
Combinatorial Inactivation of Tumor Suppressors Efficiently Initiates Lung Adenocarcinoma with Therapeutic Vulnerabilities. Cancer research 82 (8) (2022)
Philip East, Gavin P Kelly, Dhruva Biswas, Michela Marani, David C Hancock, Todd Creasy, Kris Sachsenmeier, Charles Swanton, null null, Julian Downward, Sophie de Carné Trécesson
RAS oncogenic activity predicts response to chemotherapy and outcome in lung adenocarcinoma. Nature communications 13 (1) (2022)
Karen Noble, Joanna Owens, Fabrice André, Samuel F Bakhoum, Sherene Loi, Hans Christian Reinhardt, David Tuveson, Charles Swanton
Securing the future of the clinician-scientist. Nature cancer 1 (2) (2022)
Imran Noorani, Paul S Mischel, Charles Swanton
Leveraging extrachromosomal DNA to fine-tune trials of targeted therapy for glioblastoma: opportunities and challenges. Nature reviews. Clinical oncology 19 (11) (2022)
Christine A Iacobuzio-Donahue, Kevin Litchfield, Charles Swanton
Intratumor heterogeneity reflects clinical disease course. Nature cancer 1 (1) (2022)
William Grey, Ana Rio-Machin, Pedro Casado, Eva Grönroos, Sara Ali, Juho J Miettinen, Findlay Bewicke-Copley, Alun Parsons, Caroline A Heckman, Charles Swanton, Pedro Rodriguez Cutillas, John G Gribben, Jude Fitzgibbon, Dominique Bonnet
CKS1 inhibition depletes leukemic stem cells and protects healthy hematopoietic stem cells in acute myeloid leukemia. Science translational medicine 14 (650) (2022)
Filipe Correia Martins, Dominique-Laurent Couturier, Ines de Santiago, Carolin Margarethe Sauer, Maria Vias, Mihaela Angelova, Deborah Sanders, Anna Piskorz, James Hall, Karen Hosking, Anumithra Amirthanayagam, Sabina Cosulich, Larissa S Carnevalli, Barry R Davies, Thomas B K Watkins, Ionut-Gabriel Funingana, Helen Bolton, Krishnayan Haldar, John Latimer, Peter Baldwin, Robin Crawford, Matthew D Eldridge, Bristi Basu, Mercedes Jimenez-Linan, Andrew W Mcpherson, Nicholas McGranahan, Kevin Litchfield, Sohrab P Shah, Iain A McNeish, Carlos Caldas, Gerard I Evan, Charles Swanton, James D Brenton
Clonal somatic copy number altered driver events inform drug sensitivity in high-grade serous ovarian cancer. Nature communications 13 (1) (2022)
Chris Bailey, James R M Black, James L Reading, Kevin Litchfield, Samra Turajlic, Nicholas McGranahan, Mariam Jamal-Hanjani, Charles Swanton
Tracking Cancer Evolution through the Disease Course. Cancer discovery 11 (4) (2022)
King L Hung, Jens Luebeck, Siavash R Dehkordi, Caterina I Colón, Rui Li, Ivy Tsz-Lo Wong, Ceyda Coruh, Prashanthi Dharanipragada, Shirley H Lomeli, Natasha E Weiser, Gatien Moriceau, Xiao Zhang, Chris Bailey, Kathleen E Houlahan, Wenting Yang, Rocio Chamorro González, Charles Swanton, Christina Curtis, Mariam Jamal-Hanjani, Anton G Henssen, Julie A Law, William J Greenleaf, Roger S Lo, Paul S Mischel, Vineet Bafna, Howard Y Chang
Targeted profiling of human extrachromosomal DNA by CRISPR-CATCH. Nature genetics 54 (11) (2022)
Joshua T Lange, John C Rose, Celine Y Chen, Yuriy Pichugin, Liangqi Xie, Jun Tang, King L Hung, Kathryn E Yost, Quanming Shi, Marcella L Erb, Utkrisht Rajkumar, Sihan Wu, Sabine Taschner-Mandl, Marie Bernkopf, Charles Swanton, Zhe J Liu, Weini Huang, Howard Y Chang, Vineet Bafna, Anton G Henssen, Benjamin Werner, Paul S Mischel
The evolutionary dynamics of extrachromosomal DNA in human cancers. Nature genetics 54 (10) (2022)
Shaolong Cao, Jennifer R Wang, Shuangxi Ji, Peng Yang, Yaoyi Dai, Shuai Guo, Matthew D Montierth, John Paul Shen, Xiao Zhao, Jingxiao Chen, Jaewon James Lee, Paola A Guerrero, Nicholas Spetsieris, Nikolai Engedal, Sinja Taavitsainen, Kaixian Yu, Julie Livingstone, Vinayak Bhandari, Shawna Marie Hubert, Najat C Daw, P Andrew Futreal, Eleni Efstathiou, Bora Lim, Andrea Viale, Jianjun Zhang, Matti Nykter, Bogdan A Czerniak, Powel H Brown, Charles Swanton, Pavlos Msaouel, Anirban Maitra, Edmund S Kopetz, Peter J Campbell, Terence P Speed, Paul C Boutros, Hongtu Zhu, Alfonso Urbanucci, Jonas Demeulemeester, Peter Van Loo, Wenyi Wang
Estimation of tumor cell total mRNA expression in 15 cancer types predicts disease progression. Nature biotechnology 40 (11) (2022)
Tom L Kaufmann, Marina Petkovic, Thomas B K Watkins, Emma C Colliver, Sofya Laskina, Nisha Thapa, Darlan C Minussi, Nicholas E Navin, Charles Swanton, Peter Van Loo, Kerstin Haase, Maxime Tarabichi, Roland F Schwarz
MEDICC2: whole-genome doubling aware copy-number phylogenies for cancer evolution. Genome biology 23 (1) (2022)
Annika Fendler, Lewis Au, Scott T C Shepherd, Fiona Byrne, Maddalena Cerrone, Laura Amanda Boos, Karolina Rzeniewicz, William Gordon, Benjamin Shum, Camille L Gerard, Barry Ward, Wenyi Xie, Andreas M Schmitt, Nalinie Joharatnam-Hogan, Georgina H Cornish, Martin A Pule, Leila Mekkaoui, Kevin W Ng, Eleanor Carlyle, Kim Edmonds, Lyra Del Rosario, Sarah Sarker, Karla Lingard, Mary Mangwende, Lucy Holt, Hamid Ahmod, Richard Stone, Camila Araujo De Carvalho Gomes, Helen R Flynn, Ana Agua-Doce, Philip Hobson, Simon Caidan, Michael Howell, Mary Y Wu, Robert Goldstone, Margaret Crawford, Laura Cubitt, Harshil Patel, Mike Gavrielides, Emma Nye, Ambrosius P Snijders, James I MacRae, Jérôme Nicod, Firza Gronthoud, Robyn L Shea, Christina Messiou, David Cunningham, Ian Chau, Naureen Starling, Nicholas Turner, Liam Welsh, Nicholas van As, Robin L Jones, Joanne Droney, Susana Banerjee, Kate C Tatham, Shaman Jhanji, Mary O'Brien, Olivia Curtis, Kevin J Harrington, Shreerang Bhide, Jessica Bazin, Anna Robinson, Clemency Stephenson, Tim Slattery, Yasir Khan, Zayd Tippu, Isla Leslie, Spyridon Gennatas, Alicia Okines, Alison Reid, Kate Young, Andrew J S Furness, Lisa M Pickering, Sonia Gandhi, Steven J Gamblin, Charles Swanton, null null, Emma Nicholson, Sacheen Kumar, Nadia Yousaf, Katalin Andrea Wilkinson, Anthony Swerdlow, Ruth Harvey, George Kassiotis, James Larkin, Robert J Wilkinson, Samra Turajlic, null null
Functional antibody and T cell immunity following SARS-CoV-2 infection, including by variants of concern, in patients with cancer: the CAPTURE study. Nature cancer 2 (12) (2021)
Febe van Maldegem, Karishma Valand, Megan Cole, Harshil Patel, Mihaela Angelova, Sareena Rana, Emma C Colliver, Katey S S Enfield, Nourdine Bah, Gavin P Kelly, Victoria Siu Kwan Tsang, Edurne Mugarza, Christopher Moore, Philip Hobson, Dina Levi, Miriam Molina-Arcas, Charles Swanton, Julian Downward
Characterisation of tumour microenvironment remodelling following oncogene inhibition in preclinical studies with imaging mass cytometry. Nature communications 12 (1) (2021)
Xiao Fu, Yue Zhao, Jose I Lopez, Andrew Rowan, Lewis Au, Annika Fendler, Steve Hazell, Hang Xu, Stuart Horswell, Scott T C Shepherd, Charlotte E Spencer, Lavinia Spain, Fiona Byrne, Gordon W H Stamp, Tim O'Brien, David Nicol, Marcellus Augustine, Ashish Chandra, Sarah Rudman, Antonia Toncheva, Andrew J S Furness, Lisa M Pickering, Santosh Kumar, Dow-Mu Koh, Christina Messiou, Derfel Ap Dafydd, Matthew R Orton, Simon J Doran, James Larkin, Charles Swanton, Erik Sahai, Kevin Litchfield, Samra Turajlic, null null, Paul A Bates
Spatial patterns of tumour growth impact clonal diversification in a computational model and the TRACERx Renal study. Nature ecology & evolution 6 (1) (2021)
Annika Fendler, Scott T C Shepherd, Lewis Au, Katalin Andrea Wilkinson, Mary Y Wu, Fiona Byrne, Maddalena Cerrone, Andreas M Schmitt, Nalinie Joharatnam-Hogan, Benjamin Shum, Zayd Tippu, Karolina Rzeniewicz, Laura Amanda Boos, Ruth Harvey, Eleanor Carlyle, Kim Edmonds, Lyra Del Rosario, Sarah Sarker, Karla Lingard, Mary Mangwende, Lucy Holt, Hamid Ahmod, Justine Korteweg, Tara Foley, Jessica Bazin, William Gordon, Taja Barber, Andrea Emslie-Henry, Wenyi Xie, Camille L Gerard, Daqi Deng, Emma C Wall, Ana Agua-Doce, Sina Namjou, Simon Caidan, Mike Gavrielides, James I MacRae, Gavin P Kelly, Kema Peat, Denise Kelly, Aida Murra, Kayleigh Kelly, Molly O'Flaherty, Lauren Dowdie, Natalie Ash, Firza Gronthoud, Robyn L Shea, Gail Gardner, Darren Murray, Fiona Kinnaird, Wanyuan Cui, Javier Pascual, Simon Rodney, Justin Mencel, Olivia Curtis, Clemency Stephenson, Anna Robinson, Bhavna Oza, Sheima Farag, Isla Leslie, Aljosja Rogiers, Sunil Iyengar, Mark Ethell, Christina Messiou, David Cunningham, Ian Chau, Naureen Starling, Nicholas Turner, Liam Welsh, Nicholas van As, Robin L Jones, Joanne Droney, Susana Banerjee, Kate C Tatham, Mary O'Brien, Kevin Harrington, Shreerang Bhide, Alicia Okines, Alison Reid, Kate Young, Andrew J S Furness, Lisa M Pickering, Charles Swanton, null null, Sonia Gandhi, Steven J Gamblin, David L V Bauer, George Kassiotis, Sacheen Kumar, Nadia Yousaf, Shaman Jhanji, Emma Nicholson, Michael Howell, Susanna Walker, Robert J Wilkinson, James Larkin, Samra Turajlic, null null
Adaptive immunity and neutralizing antibodies against SARS-CoV-2 variants of concern following vaccination in patients with cancer: the CAPTURE study. Nature cancer 2 (12) (2021)
Yue Zhao, Xiao Fu, Jose Ignacio López, Andrew Rowan, Lewis Au, Annika Fendler, Steve Hazell, Hang Xu, Stuart Horswell, Scott T C Shepherd, Lavinia Spain, Fiona Byrne, Gordon Stamp, Tim O'Brien, David Nicol, Marcellus Augustine, Ashish Chandra, Sarah Rudman, Antonia Toncheva, Lisa M Pickering, Erik Sahai, James Larkin, Paul A Bates, Charles Swanton, Samra Turajlic, null null, Kevin Litchfield
Selection of metastasis competent subclones in the tumour interior. Nature ecology & evolution 5 (7) (2021)
Emiliano Maiani, Giacomo Milletti, Francesca Nazio, Søs Grønbæk Holdgaard, Jirina Bartkova, Salvatore Rizza, Valentina Cianfanelli, Mar Lorente, Daniele Simoneschi, Miriam Di Marco, Pasquale D Acunzo, Luca Di Leo, Rikke Rasmussen, Costanza Montagna, Marilena Raciti, Cristiano De Stefanis, Estibaliz Gabicagogeascoa, Gergely Rona, Nélida Salvador, Emanuela Pupo, Joanna Maria Merchut-Maya, Colin J Daniel, Marianna Carinci, Valeriana Cesarini, Alfie O'sullivan, Yeon-Tae Jeong, Matteo Bordi, Francesco Russo, Silvia Campello, Angela Gallo, Giuseppe Filomeni, Letizia Lanzetti, Rosalie C Sears, Petra Hamerlik, Armando Bartolazzi, Robert Edward Hynds, David R Pearce, Charles Swanton, Michele Pagano, Guillermo Velasco, Elena Papaleo, Daniela De Zio, Apolinar Maya-Mendoza, Franco Locatelli, Jiri Bartek, Francesco Cecconi
AMBRA1 regulates cyclin D to guard S-phase entry and genomic integrity. Nature 592 (7856) (2021)

Charles Swanton.css-eqlu8i{font-size:small;padding-left:4px;}

Publication Activity (10 Years)

Top Topics

Top Venues

Charles Swanton