Increased Insulin Secretion and Glucose Effectiveness in Obese Patients with Type 2 Diabetes following Bariatric Surgery.

Roberto Visentin Katrine Brodersen Bjørn Richelsen Niels Møller Chiara Dalla Man Andreas Kristian Petersen Jan Abrahamsen Jens Juul Holst Michael Festersen Nielsen

Published in: Journal of diabetes research (2023)

These results demonstrate that the early improvement in glucose tolerance in obese T2D after RYGB and SG surgeries is attributable mainly to increased insulin secretion and glucose effectiveness, while insulin sensitivity seems to play only a minor role. This trial is registered with NCT02713555.

Keyphrases

weight loss
bariatric surgery
obese patients
roux en y gastric bypass
randomized controlled trial
adipose tissue
systematic review
metabolic syndrome
blood glucose
type diabetes
study protocol
clinical trial
phase iii
glycemic control
phase ii
open label
skeletal muscle