Interleukin 13 (IL-13) alters hypoxia-associated genes and upregulates CD73.
Syed Muaz KhalilIsaac BernsteinHeather KulagaNaina GourNicholas R RowanStephane LajoieAndrew P LanePublished in: International forum of allergy & rhinology (2020)
Our data suggests that IL-13 can induce hypoxia signaling pathway genes leading to surface expression of CD73, which has an anti-inflammatory effect.
Keyphrases
- signaling pathway
- anti inflammatory
- genome wide
- poor prognosis
- endothelial cells
- bioinformatics analysis
- genome wide identification
- nk cells
- electronic health record
- epithelial mesenchymal transition
- big data
- gene expression
- machine learning
- oxidative stress
- long non coding rna
- data analysis
- artificial intelligence