Detection of Osteoarthritis Inflammation by Single-Photon Emission Computed Tomography Based on an Inflammation-Targeting Peptide cFLFLF.

Xinlin YangAnthony J IgnozziRui HeDi ZhuXisha WangMahendra D ChordiaDongfeng PanQuanjun Cui

Published in: Molecular imaging and biology (2021)

The radioactive probe cFLFLF-PEG-HYNIC-99mTc and SPECT imaging are effective for detecting and monitoring inflammation during OA progression by targeting Fpr1 expression in the knee joint.

Keyphrases

oxidative stress
computed tomography
poor prognosis
knee osteoarthritis
high resolution
magnetic resonance imaging
rheumatoid arthritis
drug delivery
positron emission tomography
magnetic resonance
contrast enhanced
long non coding rna
image quality
dual energy