Targeting blood brain barrier-Remote ischemic conditioning alleviates cognitive impairment in female APP/PS1 rats.

Yuxuan MaWuxiang SunJing BaiFujia GaoHaoran MaHuiyu LiuJiewei HuChao XuXin ZhangZixuan LiuTao YuanChenxu SunYuanyuan HuangRuimin Wang

Published in: CNS neuroscience & therapeutics (2024)

Chronic RIC intervention exerts vascular and neuroprotective roles, suggesting that RIC could be a promising therapeutic strategy targeting the BBB and NVU during AD development.

Keyphrases

blood brain barrier
cerebral ischemia
cognitive impairment
cancer therapy
randomized controlled trial
mouse model
ischemia reperfusion injury