A randomised crossover trial of tezacaftor-ivacaftor for gut dysfunction in cystic fibrosis with magnetic resonance imaging (MRI) outcomes: a pilot study.
Christabella NgNeele S DellschaftCaroline HoadLuca MarcianiRobin SpillerColin CrooksTrevor Alexander HillAlex MenysJochen G MainzHelen BarrPenny A GowlandGiles MajorAlan Robert SmythPublished in: NIHR open research (2024)
NCT04006873 (02/07/2019).
Keyphrases
- cystic fibrosis
- magnetic resonance imaging
- open label
- phase iii
- contrast enhanced
- clinical trial
- double blind
- placebo controlled
- phase ii
- study protocol
- pseudomonas aeruginosa
- lung function
- computed tomography
- diffusion weighted imaging
- randomized controlled trial
- oxidative stress
- magnetic resonance
- adipose tissue
- type diabetes
- metabolic syndrome
- weight loss