Oncogenic roles of GPR176 in breast cancer: a potential marker of aggressiveness and a potential target of gene therapy.

Wen-Jing YunHang XueNing YangLi-Jun XiaoHong-Zhi SunHua-Chuan Zheng

Published in: Clinical & translational oncology : official publication of the Federation of Spanish Oncology Societies and of the National Cancer Institute of Mexico (2023)

These results indicate that GPR176 might be involved in the tumorigenesis and subsequent progression of breast cancer by deteriorating aggressive phenotypes. It might be utilized as a potential biomarker to indicate the aggressive behaviors and poor prognosis of breast cancer and a potential target of genetic therapy.

Keyphrases

poor prognosis
gene therapy
long non coding rna
human health
gene expression
transcription factor
stem cells
young adults
smoking cessation
dna methylation
climate change
copy number