Low-Dose Aspirin for the Primary Prevention of Cardiovascular Disease in Diabetic Individuals: A Meta-Analysis of Randomized Control Trials and Trial Sequential Analysis.
Ming-Shiun LinChien-Hsing LeeChin LinYi-Fen ZouChieh-Hua LuChang-Hsun HsiehCho-Hao LeePublished in: Journal of clinical medicine (2019)
We suggested the use of low-dose aspirin as the primary prevention strategy for CVD in diabetes, particularly in an older population. The absolute benefits were largely counterbalanced by the bleeding hazard.
Keyphrases
- low dose
- cardiovascular disease
- type diabetes
- phase iii
- high dose
- phase ii
- open label
- double blind
- clinical trial
- study protocol
- placebo controlled
- cardiovascular events
- glycemic control
- physical activity
- atrial fibrillation
- middle aged
- randomized controlled trial
- community dwelling
- cardiovascular risk factors
- antiplatelet therapy
- coronary artery disease
- data analysis