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Myxopapillary Ependymoma of Lumbar Soft Tissue: A Case Report With Gene Expression Evaluation.

Ksenia V ShelekhovaVitaly V EgorenkovValery A KheinsteinAnastasia M KonstantinovaAglaya IyevlevaEvgeny N ImyanitovMarina V MatskoDmitry E Matsko
Published in: International journal of surgical pathology (2017)
Primary extraspinal myxopapillary ependymoma (MPE) is an exceptionally rare lesion that is mainly located in the subcutaneous sacrococcygeal region. We describe the first case of MPE that presented as an intramuscular tumor mass located in the lumbar area. Absence of the visible connection with the spinal cord and lack of any other tumors in the reported case argue for the primary ectopic origin of the MPE. The differential diagnosis of MPE is discussed. Additionally, we evaluated the expression level of molecular biomarkers that have a prognostic value in central nervous system tumors.
Keyphrases
  • gene expression
  • spinal cord
  • minimally invasive
  • soft tissue
  • poor prognosis
  • dna methylation
  • spinal cord injury
  • neuropathic pain
  • cerebrospinal fluid