SHORT CHAIN FATTY ACIDS MITIGATE OSTEOCLAST-MEDIATED ARTHRITIC BONE REMODELLING.
Katharine Lu YangBriana J MullinsAlannah LejeuneEllie IvanovaJong ShinSofia BajwaRichard PossematoKen CadwellJose U ScherSergei B KoralovPublished in: Arthritis & rheumatology (Hoboken, N.J.) (2023)
We demonstrated how gut microbiota-derived SCFAs can regulate distal pathology, i.e., osteoporosis, and identified a potential therapeutic option for restoring bone density in rheumatic disease, further highlighting the critical role of the gut-bone axis in these disorders.