Tailoring Therapeutic Strategies in Non-Small-Cell Lung Cancer: The Role of Genetic Mutations and Programmed Death Ligand-1 Expression in Survival Outcomes.

Nobuaki KobayashKenji MiuraAyami KanekoHiromi MatsumotoKohei SomekawaTomofumi HiroseYukihito KajitaAnna TanakaShuhei TeranishiYu SairenjiHidetoshi KawashimaKentaro YumotoToshinori TsukaharaNobuhiko FukudaRyuichi NishihiraMakoto KudoNaoki MiyazawaTakeshi Kaneko

Published in: Cancers (2023)

This study underscores the efficacy of targeted therapies and the critical role of comprehensive molecular diagnostics and PD-L1 expression in affecting OS in NSCLC patients, advocating for their integration into routine clinical practice.

Keyphrases

clinical practice
end stage renal disease
newly diagnosed
ejection fraction
chronic kidney disease
poor prognosis
prognostic factors
peritoneal dialysis
genome wide
binding protein
long non coding rna
copy number
dna methylation