Is there a link between heart rate variability and cognitive decline? A cross-sectional study on patients with mild cognitive impairment and cognitively healthy controls.

Bernhard Grässler Milos Dordevic Sabine Darius Fabian Herold Giuseppe Forte Corinna Langhans Nicole Halfpaap Patrick Müller Wenzel Glanz Estélio Henrique Martin Dantas Irina Böckelmann Notger G Müller Anita Hökelmann

Published in: Arquivos de neuro-psiquiatria (2023)

The results support the presence of autonomic dysfunction at the early stage of cognitive impairment. Heart rate variability could help in the prediction of cognitive decline as a noninvasive biomarker or as a tool to monitor the effectiveness of therapy and prevention of neurodegenerative diseases.

Keyphrases

heart rate variability
cognitive decline
mild cognitive impairment
early stage
cognitive impairment
heart rate
randomized controlled trial
systematic review
oxidative stress
physical activity
risk factors
stem cells
radiation therapy
mesenchymal stem cells
cell therapy
bone marrow