Comprehensive analysis indicated that NDE1 is a potential biomarker for pan-cancer and promotes bladder cancer progression.

Peihan WangJinzhuo NingWu ChenFan ZouWeimin YuTing RaoFan Cheng

Published in: Cancer medicine (2024)

High expression of NDE1 is present in a variety of tumours, which is linked to a bad prognosis for cancer. Knockdown of NDE1 inhibited the proliferation, invasion and metastasis of bladder cancer cells, and promoted the apoptosis. For a number of malignancies, NDE1 may be a biomarker for immunotherapy and prognosis.

Keyphrases

papillary thyroid
squamous cell
poor prognosis
oxidative stress
spinal cord injury
squamous cell carcinoma
lymph node metastasis
cell death
cell migration
cell cycle arrest
cell proliferation
young adults