How are growth hormone and insulin-like growth factor-1 reported as markers for drug effectiveness in clinical acromegaly research? A comprehensive methodologic review.

Michiel Joost van Esdonk Eline J M van ZutphenFerdinand RoelfsemaAlberto M PereiraPiet H van der Graaf Nienke R Biermasz Jasper StevensJacobus Burggraaf

Published in: Pituitary (2018)

The way GH and IGF-1 are measured and reported in acromegaly research varies considerably. A consensus on how to report study results would enable better comparisons between studies, thereby improving evidence based decision making to optimize treatment in acromegaly.

Keyphrases

growth hormone
decision making
randomized controlled trial
systematic review
drug induced
case control
smoking cessation