Improvements in hematologic markers and decreases in fatigue with pegcetacoplan for patients with paroxysmal nocturnal hemoglobinuria and mild or moderate anemia (hemoglobin ≥10 g/dL) who had received eculizumab or were naive to complement inhibitors.
Jens Peter PanseNicolas DaguindauSonia OkuyamaRégis Peffault de LatourPhilippe SchafhausenNicole StraetmansMohammed Al-AdhamiEmmelie PerssonRaymond Siu Ming WongPublished in: PloS one (2024)
Trial registration numbers: PADDOCK (NCT02588833), PRINCE (NCT04085601; EudraCT, 2018-004220-11), PEGASUS (NCT03500549).